Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL6060002 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Benzoic Acid SCHEMBL148714 | 1.00 | TSHR (0.61) | TSHRDAONAPRTSRD5A2CES1 | |
| Triethylene Glycol SCHEMBL28076076 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Triethylene Glycol SCHEMBL2112665 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Pentaethylene Glycol SCHEMBL8622527 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Tetraethylene Glycol SCHEMBL9137599 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Triethylene Glycol SCHEMBL2442859 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Triethylene Glycol SCHEMBL205789 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Triethylene Glycol SCHEMBL5730892 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 | |
| Tetraethylene Glycol SCHEMBL1555416 | 0.98 | TSHR (0.58) | TSHRDAONAPRTSRD5A2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109795-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | EASTMAN CHEMICAL COMPANY (US) | 2026-04-23 | — | — | US | claimed |
| EP-4598999-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | Eastman Chemical Company (US) | 2025-08-13 | — | — | EP | claimed |
| US-20250197609-A1 | ECOFRIENDLY, BIODEGRADABLE BIOLOGICAL POLYSACCHARIDE COMPOSITION FOR PACKAGING MATERIALS | BLUE EVOLUTION, INC. (US) | 2025-06-19 | — | — | US | claimed |
| WO-2025128797-A1 | ECOFRIENDLY, BIODEGRADABLE BIOLOGICAL POLYSACCHARIDE COMPOSITION FOR PACKAGING MATERIALS | BLUE EVOLUTION, INC (US) | 2025-06-19 | — | — | WO | claimed |
| CN-119998391-A | High refractive index polyvinyl acetal resins modified with cyclic aldehydes | 伊士曼化工公司 | 2025-05-13 | — | — | CN | claimed |
| US-20250129006-A1 | PRODUCTION OF BENZOIC ACID FROM A BIOMASS | SYENSQO SA (BE) | 2025-04-24 | — | — | US | claimed |
| CN-119432278-A | Modified epoxy resin conductive adhesive and preparation method thereof | 苏州市盛锦祥电子科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119410111-A | PET flame-retardant material, preparation method thereof and preparation method of floor containing material | 爱丽家居科技股份有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-118272026-A | Bio-based polyurethane adhesive for compounding scouring pad | 无锡旺绿鸿纺织品有限公司 | 2024-07-02 | — | — | CN | claimed |
| EP-4380917-A1 | PRODUCTION OF BENZOIC ACID FROM A BIOMASS | SYENSQO SA (BE) | 2024-06-12 | — | — | EP | claimed |
| US-6291385-B1 | Catalyst for polymerization or copolymerization of olefin | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 2001-09-18 | — | — | US | claimed |
| WO-2001040320-A1 | CATALYST FOR POLYMERIZATION AND CO-POLYMERIZATION OF ETHYLENE | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 2001-06-07 | — | — | WO | claimed |
| WO-2000073356-A1 | A CATALYST FOR ETHYLENE HOMO- AND CO-POLYMERIZATION | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 2000-12-07 | — | — | WO | claimed |
| WO-2000073355-A1 | A CATALYST FOR ETHYLENE HOMO- AND CO-POLYMERIZATION | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 2000-12-07 | — | — | WO | claimed |
| US-5929133-A | FILM CONTAINING PLASTICIZER, STABILIZER, HYDROTALCITE, ANTIFOGGING AGENT AND ANTIBACTERIAL AGENT OF INORGANIC OXO-ACID SALT HAVING BEEN ION EXCHANGED WITH ANTIBACTERIAL IONS OF SILVER, COPPER, ZINC AND/OR TIN | HITACHI CHEMICAL FILTEC, INC. (JP) | 1999-07-27 | — | — | US | claimed |
| US-5676742-A | BLEND OF DIPROPYLENE GLYCOL DIBENZOATE AND DIPROPYLENE GLYCOL MONOBENZOATE | VELSICOL CHEMICAL CORPORATION (US) | 1997-10-14 | — | — | US | claimed |
| WO-1997016481-A1 | MONO AND DIBENZOATE ESTER BLENDS AS CAULK PLASTICIZERS THAT ARE BIORESISTANT TO FUNGAL GROWTH | VELSICOL CHEMICAL CORPORATION (US) | 1997-05-09 | — | — | WO | claimed |
| US-5459116-A | Magnesium, titanium, halogen and hydroxyalkyl ester compounds; stereospecific, bulk density; polyethylene | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 1995-10-17 | — | — | US | claimed |
| US-4568146-A | AMORPHOUS POLYMER CORE CONTAINING PLASTICIZER AND CLADDING TO PREVENT CROSS-MIGRATION | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1986-02-04 | — | — | US | claimed |
| US-4132882-A | Process and apparatus for fixing toner with heat and a fixing agent | CANON KABUSHIKI KAISHA (JP) | 1979-01-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109795-A1 | HIGH REFRACTIVE INDEX POLYVINYL ACETAL RESINS MODIFIED WITH CYCLIC ALDEHYDES | TRIM4, TRIM58, TRA2B | TSHR 3046/4885DAO 3021/4885NAPRT 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.