⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068685 | 0.80 | — | — | |
| SCHEMBL3052942 | 0.80 | — | — | |
| SCHEMBL293931 | 0.80 | — | — | |
| SCHEMBL5168265 | 0.79 | USP7 (0.56) | — | |
| SCHEMBL4966007 | 0.78 | — | — | |
| SCHEMBL294099 | 0.78 | POLB (0.41) | — | |
| SCHEMBL15921055 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL2583653 | 0.78 | ALDH1A1 (0.49) | — | |
| SCHEMBL21853882 | 0.78 | ALDH1A1 (0.38) | — | |
| SCHEMBL27395757 | 0.78 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12565493-B2 | Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one | BASF SE (DE) | 2026-03-03 | — | — | US | claimed |
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | BASF SE (DE) | 2025-07-22 | — | — | US | claimed |
| CN-114555568-B | Preparation of 2-chloro-1- (2-chlorothiazol-5-yl) ethanone | 巴斯夫欧洲公司 | 2025-01-24 | — | — | CN | claimed |
| US-20240101547-A1 | METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | BASF SE (DE) | 2024-03-28 | — | — | US | claimed |
| US-20240051929-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2024-02-15 | — | — | US | claimed |
| EP-4281441-A1 | METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | BASF SE (DE) | 2023-11-29 | — | — | EP | claimed |
| EP-4038056-B1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2023-11-08 | — | — | EP | claimed |
| CN-116783169-A | Process for preparing 2- [2- (2-chlorothiazol-5-yl) -2-oxoethyl ] sulfanyl-6-hydroxy-3-methyl-5-phenylpyrimidin-4-one | 巴斯夫欧洲公司 | 2023-09-19 | — | — | CN | claimed |
| CN-114555568-A | Preparation of 2-chloro-1- (2-chlorothiazol-5-yl) ethanone | 巴斯夫欧洲公司 | 2022-05-27 | — | — | CN | claimed |
| WO-2021063880-A1 | PREPARATION OF 2-CHLORO-1-(2-CHLOROTHIAZOL-5-YL)ETHANONE | BASF SE (DE) | 2021-04-08 | — | — | WO | claimed |
| US-12565493-B2 | Method for preparing 2-[2-(2-chlorothiazol-5-yl)-2-oxo-ethyl]sulfanyl-6-hydroxy-3-methyl-5-phenyl-pyrimidin-4-one | BASF SE (DE) | 2026-03-03 | — | — | US | disclosed |
| US-12516030-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | BASF SE (DE) | 2026-01-06 | — | — | US | disclosed |
| US-12365657-B2 | Preparation of 2-chloro-1-(2-chlorothiazol-5-yl)ethanone | BASF SE (DE) | 2025-07-22 | — | — | US | disclosed |
| CN-114555568-B | Preparation of 2-chloro-1- (2-chlorothiazol-5-yl) ethanone | 巴斯夫欧洲公司 | 2025-01-24 | — | — | CN | disclosed |
| US-20240101547-A1 | METHOD FOR PREPARING 2-[2-(2-CHLOROTHIAZOL-5-YL)-2-OXO-ETHYL]SULFANYL-6-HYDROXY-3-METHYL-5-PHENYL-PYRIMIDIN-4-ONE | BASF SE (DE) | 2024-03-28 | — | — | US | disclosed |
| US-20070093498-A1 | Thieno-pyrimidine compounds having fungicidal activity | BREWSTER WILLIAM K | 2007-04-26 | — | — | US | disclosed |
| WO-2007046809-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2006066172-A1 | AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE | AMGEN, INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006047397-A1 | THIENO-PYRIMIDINE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060089370-A1 | Thieno-pyrimidine compounds having fungicidal activity | BREWSTER WILLIAM K | 2006-04-27 | — | — | US | disclosed |