Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774807 | 0.82 | KDM4E (0.39) | ALDH1A1KMT2AFFAR2HCAR2LMNA | |
| SCHEMBL2030310 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL285761 | 0.80 | CDC7 (0.57) | ALDH1A1NPSR1L3MBTL1MAPK1KDM4E | |
| SCHEMBL14141968 | 0.80 | FFAR2 (0.39) | ALDH1A1KMT2AFFAR2LMNAL3MBTL1 | |
| SCHEMBL293931 | 0.79 | — | — | |
| SCHEMBL21448921 | 0.79 | FFAR2 (0.43) | ALDH1A1KMT2AFFAR2HCAR2LMNA | |
| SCHEMBL1107386 | 0.78 | HCAR2 (0.68) | ALDH1A1FFAR2HCAR2LMNAPPARG | |
| SCHEMBL4292895 | 0.78 | HCAR2 (0.42) | ALDH1A1FFAR2HCAR2LMNAPPARG | |
| SCHEMBL472995 | 0.78 | CSNK2A2 (0.42) | ALDH1A1FFAR2HCAR2LMNAPPARG | |
| SCHEMBL2057950 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12384773-B2 | Thiazole compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-12312345-B2 | Fluoroalkyl-oxadiazoles and uses thereof | TENAYA THERAPEUTICS, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| WO-2025096979-A1 | THIAZOLE COMPOUNDS AS KIT INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| US-20250145606-A1 | THIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-05-08 | — | — | US | disclosed |
| CN-119751456-A | Spiro compounds | C4医药公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-112312904-B | Spiro compounds | C4医药公司 | 2025-01-07 | — | — | CN | disclosed |
| US-20240182462-A1 | FLUOROALKYL-OXADIAZOLES AND USES THEREOF | TENAYA THERAPEUTICS, INC. | 2024-06-06 | — | — | US | disclosed |
| CN-115003663-B | Novel heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-04-30 | — | — | CN | disclosed |
| US-11926622-B2 | Fluoroalkyl-oxadiazoles and uses thereof | TENAYA THERAPEUTICS, INC. (US) | 2024-03-12 | — | — | US | disclosed |
| EP-3715346-B1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA FARBER CANCER INST INC (US) | 2024-01-03 | — | — | EP | disclosed |
| US-20040192729-A1 | Carboxylic acids and the esters thereof, pharmaceutical compositions thereto and processes for the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-09-30 | — | — | US | disclosed |
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0142057-A2 | Thiazoloquinazoline derivatives, their preparation and pharmaceutical compositions containing same | F. HOFFMANN-LA ROCHE AG (CH) | 1985-05-22 | — | — | EP | disclosed |
| EP-0006114-B1 | 7-METHOXY-5-OXO-5H-THIAZOLO(2,3-B)QUINAZOLIN-2-CARBOXYLIC ACID AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-04-07 | — | — | EP | disclosed |
| US-4282360-A | ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4282360-A | ANTIALLERGENS | HOFFMANN-LA ROCHE INC. (US) | 1981-08-04 | — | — | US | disclosed |
| EP-0027268-A2 | Quinazoline derivatives, process and intermediates for their preparation, medicaments containing them and their pharmaceutical use | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-22 | — | — | EP | disclosed |
| EP-0006114-A1 | 7-Methoxy-5-oxo-5H-thiazolo(2,3-b)quinazolin-2-carboxylic acid and its pharmaceutically acceptable salts, process for their preparation and medicines containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-01-09 | — | — | EP | disclosed |
| US-4168380-A | ANTIALLERGEN | HOFFMANN-LA ROCHE INC. (US) | 1979-09-18 | — | — | US | disclosed |
| US-4168380-A | ANTIALLERGEN | HOFFMANN-LA ROCHE INC. (US) | 1979-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192729-A1 | Carboxylic acids and the esters thereof, pharmaceutical compositions thereto and processes for the preparation thereof | NPY1R, ADCY1, SRD5A1 | ALDH1A1 102/4885KMT2A 3049/4885FFAR2 208/4885 |
| US-12384773-B2 | Thiazole compounds and methods of use thereof | TPMT, CYP11B2, ABAT | ALDH1A1 198/4885KMT2A 4374/4885FFAR2 1832/4885 |
| US-11926622-B2 | Fluoroalkyl-oxadiazoles and uses thereof | HDAC6, HDAC1, HDAC3 | ALDH1A1 134/4885KMT2A 636/4885FFAR2 1844/4885 |
| US-20240182462-A1 | FLUOROALKYL-OXADIAZOLES AND USES THEREOF | HDAC6, HDAC1, HDAC3 | ALDH1A1 134/4885KMT2A 636/4885FFAR2 1844/4885 |
| US-12312345-B2 | Fluoroalkyl-oxadiazoles and uses thereof | HDAC6, HDAC1, HDAC3 | ALDH1A1 134/4885KMT2A 636/4885FFAR2 1844/4885 |
| US-20250145606-A1 | THIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | TPMT, CYP11B2, ABAT | ALDH1A1 198/4885KMT2A 4374/4885FFAR2 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.