Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20579832 | 0.84 | CYP1A2 (0.66) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL20579758 | 0.84 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL20579760 | 0.83 | MAPK1 (0.74) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL20579820 | 0.82 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL21097067 | 0.81 | SMN1; SMN2 (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL20579799 | 0.81 | SMN1; SMN2 (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL20579783 | 0.80 | CYP1A2 (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL20580270 | 0.77 | SMN1; SMN2 (0.55) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL14740847 | 0.76 | CYP1A2 (0.70) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 | |
| SCHEMBL20579779 | 0.76 | CYP1A2 (0.77) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-20180354948-A1 | IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2018-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354948-A1 | IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE DERIVATIVE AND PREPARATION METHOD THEREOF | AZI2, AOC3, AOC2 | CYP1A2 10/4885CYP2C9 219/4885CYP2C19 140/4885 |
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | AZI2, AOC3, AOC2 | CYP1A2 10/4885CYP2C9 219/4885CYP2C19 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.