Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MARK4 | Q96L34 | 4/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20579758 | 0.91 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL20579832 | 0.89 | CYP1A2 (0.66) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL21097067 | 0.87 | SMN1; SMN2 (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL20579799 | 0.87 | SMN1; SMN2 (0.60) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL20579833 | 0.86 | NPC1 (0.54) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNK3 | |
| SCHEMBL20580270 | 0.85 | SMN1; SMN2 (0.55) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL20579955 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNK3 | |
| SCHEMBL20579820 | 0.82 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL20580266 | 0.80 | CYP1A2 (0.57) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL22614998 | 0.78 | TUBB4A (0.57) | CYP1A2CYP2C9CYP2C19SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2019-06-18 | — | — | US | disclosed |
| US-20180354948-A1 | IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2018-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354948-A1 | IMIDAZO[1,2-A]PYRIDINE-3-CARBOXYLATE DERIVATIVE AND PREPARATION METHOD THEREOF | AZI2, AOC3, AOC2 | CYP1A2 10/4885CYP2C9 219/4885CYP2C19 140/4885 |
| US-10323033-B2 | Imidazo[1,2-A]pyridine-3-carboxylate derivative and preparation method thereof | AZI2, AOC3, AOC2 | CYP1A2 10/4885CYP2C9 219/4885CYP2C19 140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.