SCHEMBL20580607

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30610188	1.00	IDO1 (0.42)	IDO1TDO2CCNA2CDK2ERN1
	SCHEMBL17731756	0.89	IDO1 (0.41)	IDO1TDO2CCNA2CDK2TRPV1
	SCHEMBL31687246	0.85	JAK1 (0.43)	IDO1TDO2CCNA2CDK2TRPV1
	SCHEMBL29092528	0.83	METAP2 (0.47)	IDO1TDO2CDK2TRPV1
	SCHEMBL30602751	0.83	METAP2 (0.47)	IDO1TDO2CDK2TRPV1
	SCHEMBL17739283	0.79	SMO (0.42)	IDO1TDO2ERN1
	SCHEMBL28459521	0.77	IDO1 (0.38)	IDO1TDO2CCNA2CDK2TRPV1
	SCHEMBL17739098	0.77	FASN (0.42)	IDO1TDO2TRPV1
	SCHEMBL17731753	0.77	METAP2 (0.42)	IDO1TDO2CDK2TRPV1
	SCHEMBL17738576	0.76	JAK2 (0.51)	IDO1TDO2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.