Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 7/20 | 0.41 |
| ▸ | MGAM | O43451 | 4/20 | 0.36 |
| ▸ | SI | P14410 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27175327 | 0.95 | LGALS8 (0.40) | LGALS8MGAMSIGAAALDH1A1 | |
| SCHEMBL15267647 | 0.92 | LGALS8 (0.43) | LGALS8MGAMSIGAAALDH1A1 | |
| SCHEMBL13772540 | 0.92 | LGALS8 (0.43) | LGALS8MGAMSIGAAALDH1A1 | |
| SCHEMBL16504207 | 0.86 | LGALS8 (0.43) | LGALS8GAAALDH1A1HIF1A | |
| SCHEMBL14864297 | 0.86 | LGALS8 (0.43) | LGALS8GAAALDH1A1HIF1A | |
| SCHEMBL23723836 | 0.86 | LGALS8 (0.43) | LGALS8GAAALDH1A1HIF1A | |
| SCHEMBL13482776 | 0.86 | LGALS8 (0.43) | LGALS8GAAALDH1A1HIF1A | |
| SCHEMBL17256295 | 0.86 | LGALS8 (0.43) | LGALS8GAAALDH1A1HIF1A | |
| SCHEMBL18723048 | 0.86 | LGALS8 (0.43) | LGALS8GAAALDH1A1HIF1A | |
| SCHEMBL20033536 | 0.86 | LGALS8 (0.43) | LGALS8GAAALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157138-A1 | NICOTINAMIDE ADENINE DINUCLEOTIDE ANALOGUES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2020-05-21 | — | — | US | disclosed |
| WO-2018227168-A1 | NICOTINAMIDE ADENINE DINUCLEOTIDE ANALOGUES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157138-A1 | NICOTINAMIDE ADENINE DINUCLEOTIDE ANALOGUES | NAMPT, NNT, NNMT | LGALS8 3581/4885MGAM 3208/4885SI 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.