Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.78 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.78 |
| ▸ | PRKCG | P05129 | 4/20 | 0.78 |
| ▸ | PRKCB | P05771 | 4/20 | 0.78 |
| ▸ | PRKCH | P24723 | 4/20 | 0.78 |
| ▸ | PRKCI | P41743 | 4/20 | 0.78 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.78 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.78 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.78 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.78 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.78 |
| ▸ | USP2 | O75604 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristyl Alcohol SCHEMBL7566997 | 0.93 | PRKCA (0.76) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| Acetic Acid SCHEMBL5925269 | 0.91 | PRKCA (0.77) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL18210530 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL8192421 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL2127254 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL16904300 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL21578359 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL22171801 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL892726 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL312634 | 0.90 | PRKCA (0.79) | PRKCAPRKD3PRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071333-A | CALCIUM RECEPTOR ACTIVE MOLECULES | NPS PHARMA INC (US) | 1993-04-28 | — | — | CN | claimed |
| US-20210223229-A1 | IMMUNE FUNCTION INSPECTION METHOD, CANCER PATIENT CATEGORIZATION METHOD, CANCER TREATMENT EFFICACY PREDICTION METHOD, AGENT FOR INCREASING INTRACELLULAR CALCIUM ION CONCENTRATION, AGENT FOR INCREASING SELECTIVE FUNCTION OF EFFECTOR MEMORY (EM) AND EFFECTOR (EFF) IN TUMOR TISSUE, AND METHOD FOR MONITORING EFFICACY OF CANCER DRUG | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2021-07-22 | — | — | US | disclosed |
| EP-3415908-A1 | IMMUNE FUNCTION INSPECTION METHOD, CANCER PATIENT CATEGORIZATION METHOD, CANCER TREATMENT EFFICACY PREDICTION METHOD, AGENT FOR INCREASING INTRACELLULAR CALCIUM ION CONCENTRATION, AGENT FOR INCREASING SELECTIVE FUNCTION OF EFFECTOR MEMORY (EM) AND EFFECTOR (EFF) IN TUMOR TISSUE, AND METHOD FOR MONITORING EFFICACY OF CANCER DRUG | National University Corporation Okayama University (JP) | 2018-12-19 | — | — | EP | disclosed |
| CN-101641081-B | Composition for improving skin condition containing matrine or its oxidized derivative | BIOSPECTRUM INC KR | 2012-07-04 | — | — | CN | disclosed |
| CN-102423312-A | Compositions for improving skin conditions comprising matrine or its oxidized derivatives | BIOSPECTRUM INC | 2012-04-25 | — | — | CN | disclosed |
| CN-1665524-B | Use of alanyl aminopeptidase inhibitors and pharmaceutical compositions containing said inhibitors | INST MEDIZINTECHNOLOGIE MAGDEB | 2010-08-25 | — | — | CN | disclosed |
| CN-101641081-A | Composition for improving skin condition containing matrine or its oxidized derivative | BIOSPECTRUM INC KR | 2010-02-03 | — | — | CN | disclosed |
| CN-100488533-C | An herbal composition for the treatment and remedy of bronchial respiratory difficulties | COUNCIL SCIENT IND RES (IN) | 2009-05-20 | — | — | CN | disclosed |
| CN-101123977-A | Compositions for inducing a therapeutic response | HELICONIA CORP (US) | 2008-02-13 | — | — | CN | disclosed |
| CN-1665524-A | Use of alanyl aminopeptidase inhibitors and pharmaceutical compositions containing said inhibitors | INST MEDIZINTECHNOLOGIE MAGDEB (DE) | 2005-09-07 | — | — | CN | disclosed |
| CN-1652805-A | An herbal composition for the treatment and remedy of bronchial respiratory difficulties | COUNCIL SCIENT IND RES (IN) | 2005-08-10 | — | — | CN | disclosed |
| CN-1096859-C | Combination preparation, containing cyclosporin a or FK506 or rapamycin and a xanthine derivative | HOECHST AG (DE) | 2002-12-25 | — | — | CN | disclosed |
| CN-1162919-A | Combination preparation, containing cyclosporin a or FK506 or rapamycin and a xanthine derivative | HOECHST AG (DE) | 1997-10-22 | — | — | CN | disclosed |