Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23357363 | 0.82 | PTPN2 (0.50) | TSHRPTPN2PTPN1GABRA1GABRB2 | |
| SCHEMBL1246417 | 0.78 | ACP3 (0.62) | FDPSACP3 | |
| SCHEMBL887607 | 0.75 | TSHR (0.53) | TSHRGABRA1GABRB2LMNA | |
| SCHEMBL4981071 | 0.75 | TSHR (0.53) | TSHRGABRA1GABRB2LMNA | |
| SCHEMBL8853304 | 0.75 | TSHR (0.53) | TSHRGABRA1GABRB2LMNA | |
| SCHEMBL574034 | 0.74 | TSHR (0.68) | TSHRGABRA1GABRB2LMNA | |
| SCHEMBL8583238 | 0.74 | ESR1 (0.43) | FDPS | |
| SCHEMBL20587741 | 0.73 | ACP3 (0.65) | PTPN2PTPN1ACP3 | |
| SCHEMBL3234995 | 0.73 | FDPS (0.46) | FDPSLMNAACP3 | |
| SCHEMBL980886 | 0.73 | TSHR (0.55) | TSHRGABRA1GABRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018232315-A1 | CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2018-12-20 | — | — | WO | disclosed |