Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594119 | 0.75 | HSD17B10 (0.48) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL26294667 | 0.74 | ALDH1A1 (0.50) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL20855328 | 0.71 | GPR3 (0.48) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL31313485 | 0.71 | GPR3 (0.48) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL20594339 | 0.71 | PDE10A (0.45) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL2001240 | 0.70 | KDM4E (1.00) | KDM4EALDH1A1KDM4AKDM5BKMT2A | |
| SCHEMBL22410701 | 0.68 | KDM4E (0.40) | KDM4EALDH1A1KMT2AGAAMAPT | |
| SCHEMBL19889990 | 0.68 | KDM4E (0.42) | KDM4EALDH1A1KMT2AMEN1HTT | |
| SCHEMBL30853612 | 0.67 | ESR1 (0.39) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL16111018 | 0.65 | GPR3 (0.41) | KDM4EALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018234184-A1 | PROCESS FOR THE PREPARATION OF 2,3,4-TRISUBSTITUTED QUINOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-12-27 | — | — | WO | disclosed |