Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 7/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160904 | 1.00 | HCRTR1 (0.37) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL20595261 | 0.90 | MAPT (0.38) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL21800729 | 0.90 | MAPT (0.38) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL3704769 | 0.89 | P2RX3 (0.42) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL2174735 | 0.88 | KDM4E (0.35) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL20595603 | 0.86 | ACACB (0.37) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL21800770 | 0.86 | LMNA (0.37) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL21800655 | 0.86 | ACACB (0.37) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL20595529 | 0.86 | LMNA (0.37) | HCRTR1HCRTR2KDM4ERAB9ANPC1 | |
| SCHEMBL20595495 | 0.85 | CYP1A2 (0.39) | HCRTR1HCRTR2KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018236928-A1 | HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS | UNIVERSITY OF MASSACHUSETTS (US) | 2018-12-27 | — | — | WO | disclosed |