SCHEMBL2059627

SCHEMBL2059627

O[C@@H]1[C@@H](O)[C@@H](O)C(O)(O)[C@H](O)[C@H]1O

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
APP P05067 1/20 0.42
GBA1 P04062 3/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5150816 1.00 LMNA (0.42) LMNAAPPGBA1GAA
SCHEMBL5150809 1.00 LMNA (0.42) LMNAAPPGBA1GAA
SCHEMBL27913293 0.78 LMNA (0.46) LMNAAPPGBA1GAA
SCHEMBL27895828 0.78 LMNA (0.46) LMNAAPPGBA1GAA
SCHEMBL15617775 0.77 FUCA1 (0.33)
SCHEMBL27913288 0.77
SCHEMBL439753 0.75 LMNA (0.42) LMNAAPPGBA1GAA
SCHEMBL27895821 0.72
SCHEMBL27913349 0.72
SCHEMBL2461938 0.69 LMNA (0.36) LMNAAPPGBA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108018265-A A kind of inositol oxidation enzyme mutant and its encoding gene and application 山东大学 2018-05-11 CN claimed
US-7825270-B2 Inositolphospholipids and analogues: phosphatidylinositol products and processes NUTRIMED BIOTECH (US) 2010-11-02 US claimed
WO-2007073559-A2 INOSITOLPHOSPHOLIPIDS AND ANALOGUES: PHOSPHALIDYLINOSITOL PRODUCTS AND PROCESSES NUTRIMED BIOTECH (US) 2007-06-28 WO claimed
US-20070142653-A1 Inositolphospholipids and Analogues: Phosphatidylinositol Products and Processes NUTRIMED BIOTECH (US) 2007-06-21 US claimed
EP-0730460-B1 THE USE OF AN ESTER OF INOSITOLTRISPHOSPHATE FOR THE TREATMENT OF INFLAMMATORY CONDITIONS PERSTORP AB (SE) 2002-06-12 EP claimed
US-5866557-A REDUCE TISSUE DAMAGE PERSTORP AB (SE) 1999-02-02 US claimed
US-5846957-A Use of an ester of inositoltrisphosphate for the preparing of medicaments PERSTORP AB (SE) 1998-12-08 US claimed
US-5214180-A Plant extracts, protecting hydroxy groups, solvent extraction, chromatography MEDIOLANUM FARMACEUTICI S.P.A. (IT) 1993-05-25 US claimed
EP-0516914-A2 Highly pure phosphatidylinositol of natural source useful for the treatment of central nervous system disorders and process for its preparation MEDIOLANUM FARMACEUTICI s.r.l. (IT) 1992-12-09 EP claimed
JP-5097875-A None JP disclosed
WO-2024047037-A1 COMPOSITIONS FOR PARENTERAL SUSTAINED RELEASE DELIVERY OF HYDROPHILIC DRUGS ETH Zürich (CH) 2024-03-07 WO disclosed
EP-3503880-B1 COMPOUNDS FOR TREATMENT OF INTRACTABLE EPILEPSY AND DOORS SYNDROME VIB VZW (BE) 2023-12-27 EP disclosed
CN-112135633-A Phytate for use as a biomolecule delivery or adsorption system 禾大国际股份公开有限公司 2020-12-25 CN disclosed
US-20200093843-A1 COMPOUNDS FOR TREATMENT OF INTRACTABLE EPILEPSY AND DOORS SYNDROME VIB VZW (BE) 2020-03-26 US disclosed
US-5214180-A Plant extracts, protecting hydroxy groups, solvent extraction, chromatography MEDIOLANUM FARMACEUTICI S.P.A. (IT) 1993-05-25 US disclosed
JP-H0597875-A HIGH PURITY PHOSPHATIDYLINOSITOL FROM NATURAL SOURCE USEFUL FOR TREATING CENTRAL NERVOUS SYSTEM DISORDER AND ITS PREPARATION MEDIOLANUM FARMACEUT SRL 1993-04-20 JP disclosed
EP-0516914-A2 Highly pure phosphatidylinositol of natural source useful for the treatment of central nervous system disorders and process for its preparation MEDIOLANUM FARMACEUTICI s.r.l. (IT) 1992-12-09 EP disclosed
EP-0516914-A2 Highly pure phosphatidylinositol of natural source useful for the treatment of central nervous system disorders and process for its preparation MEDIOLANUM FARMACEUTICI s.r.l. (IT) 1992-12-09 EP disclosed
WO-1991016920-A1 LIPID PRODRUGS OF SALICYLATE AND NONSTEROIDAL ANTI-INFLAMMATORY DRUGS VICAL, INC. (US) 1991-11-14 WO disclosed
US-4924023-A MEDICINE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142653-A1 Inositolphospholipids and Analogues: Phosphatidylinositol Products and Processes PLCB3, INPPL1, PLCB1 LMNA 986/4885APP 810/4885GBA1 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.