Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895828 | 1.00 | LMNA (0.46) | LMNAAPPGBA1GAAMGAM | |
| SCHEMBL2059627 | 0.78 | LMNA (0.42) | LMNAAPPGBA1GAA | |
| SCHEMBL5150809 | 0.78 | LMNA (0.42) | LMNAAPPGBA1GAA | |
| SCHEMBL5150816 | 0.78 | LMNA (0.42) | LMNAAPPGBA1GAA | |
| SCHEMBL439753 | 0.78 | LMNA (0.42) | LMNAAPPGBA1GAA | |
| SCHEMBL28140442 | 0.75 | LMNA (0.39) | LMNAAPP | |
| SCHEMBL27913607 | 0.75 | LMNA (0.39) | LMNAAPP | |
| SCHEMBL27913335 | 0.75 | LMNA (0.39) | LMNAAPP | |
| SCHEMBL2517248 | 0.72 | LMNA (0.36) | LMNAAPPGBA1GAA | |
| SCHEMBL12858512 | 0.72 | LMNA (0.36) | LMNAAPPGBA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102977145-A | Phosphoinositide compounds and their preparation method and use | UNIV NANKAI | 2013-03-20 | — | — | CN | disclosed |