Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849274 | 0.87 | ZDHHC20 (0.60) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL296003 | 0.85 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL13636033 | 0.84 | ZDHHC20 (0.67) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL6863950 | 0.81 | ZDHHC20 (0.48) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL10952688 | 0.80 | TSHR (0.68) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL167051 | 0.80 | TSHR (0.68) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| Urea SCHEMBL29002144 | 0.79 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL2612178 | 0.79 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL22675564 | 0.79 | TSHR (0.54) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 | |
| SCHEMBL35714 | 0.79 | TSHR (0.54) | ZDHHC20ZDHHC2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840136-B1 | Polymer dispersions, method for their manufacture and their application | CELANESE EMULSIONS GMBH (DE) | 2010-08-11 | — | — | EP | claimed |
| US-20220133711-A1 | CAMPTOTHECIN DERIVATIVES | IMMUNOGEN, INC. | 2022-05-05 | — | — | US | disclosed |
| WO-2020219287-A1 | CAMPTOTHECIN DERIVATIVES | IMMUNOGEN, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| EP-2953457-B1 | ERK INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2020-04-08 | — | — | EP | disclosed |
| EP-3263209-A1 | MEMBRANES COMPRISING POLYMERIC PARTICLE LAYERS | BASF SE (DE) | 2018-01-03 | — | — | EP | disclosed |
| US-9796700-B2 | ERK inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2017-10-24 | — | — | US | disclosed |
| US-20170210729-A1 | ERK INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-20170137406-A1 | ERK INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-05-18 | — | — | US | disclosed |
| US-9561228-B2 | ERK inhibitors and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2017-02-07 | — | — | US | disclosed |
| US-9504686-B2 | ERK inhibitors and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| EP-0134490-B1 | SELF-CROSS-LINKABLE COATING, IMPREGNATION AND ADHESIVE AGENT | BASF Aktiengesellschaft (DE) | 1988-01-20 | — | — | EP | disclosed |
| EP-0226129-A2 | Silver halide photographic element, photographic coating composition and process to prepare an aqueous dispersion of a hydrophobic compound | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-06-24 | — | — | EP | disclosed |
| EP-0219047-A2 | Curable polymer compositions storage-stable in an aqueous solution or dispersion, their preparation and use | BASF Aktiengesellschaft (DE) | 1987-04-22 | — | — | EP | disclosed |
| US-4637467-A | INJECTION OF N-3-OXOHYDROCARBON-SUBSTITUTED ACRYLAMIDES | PHILLIPS PETROLEUM COMPANY (US) | 1987-01-20 | — | — | US | disclosed |
| US-4332873-A | Multilayer printing plates and process for making same | HERCULES INCORPORATED (US) | 1982-06-01 | — | — | US | disclosed |
| US-4266007-A | Multilayer printing plates and process for making same | HERCULES INCORPORATED (US) | 1981-05-05 | — | — | US | disclosed |
| US-4217038-A | TERMINATED WITH POLYMERIZED ACTIVATED UNSATURATED GROUP | BAUSCH & LOMB INCORPORATED (US) | 1980-08-12 | — | — | US | disclosed |
| US-4198238-A | Photopolymerizable composition | HERCULES INCORPORATED (US) | 1980-04-15 | — | — | US | disclosed |
| US-4168173-A | UNSATURATED POLYESTERS, UNSATURATED MONOMER, BISPHENOL-EPICHLOROHYDRIN COPOLYMER THICKENER | HERCULES INCORPORATED (US) | 1979-09-18 | — | — | US | disclosed |
| US-3941836-A | SOLUBILIZERS, PLASTICIZER, UV ABSORBER | THE LUBRIZOL CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137406-A1 | ERK INHIBITORS AND USES THEREOF | MAP3K20, MAP3K1, MAPK3 | ZDHHC20 1305/4885ZDHHC2 1570/4885ALDH1A1 2838/4885 |
| US-20220133711-A1 | CAMPTOTHECIN DERIVATIVES | TOP2A, TOP2B, PCNA | ZDHHC20 4021/4885ZDHHC2 4226/4885ALDH1A1 1182/4885 |
| US-20170210729-A1 | ERK INHIBITORS AND USES THEREOF | MAP3K20, MAP3K1, MAPK3 | ZDHHC20 1305/4885ZDHHC2 1570/4885ALDH1A1 2838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.