⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10171943 | 0.98 | KDM4E (0.31) | — | |
| SCHEMBL16146534 | 0.82 | XDH (0.37) | — | |
| SCHEMBL15132052 | 0.80 | PDPK1 (0.33) | — | |
| SCHEMBL16145777 | 0.79 | ALDH1A1 (0.30) | — | |
| SCHEMBL12844134 | 0.79 | HEXA (0.37) | — | |
| SCHEMBL12948554 | 0.79 | KDM4E (0.31) | — | |
| SCHEMBL16146290 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL16145905 | 0.79 | CSNK2A1 (0.33) | — | |
| SCHEMBL5066802 | 0.79 | ADORA1 (0.37) | — | |
| SCHEMBL16146865 | 0.79 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210107910-A1 | Compositions and Methods of Using the Same for Treatment of Neurodegenerative and Mitochondrial Disease | MITOKININ, INC. (US) | 2021-04-15 | — | — | US | disclosed |
| US-10851109-B2 | Compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease | MITOKININ LLC (US) | 2020-12-01 | — | — | US | disclosed |
| US-20190194207-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ INC (US) | 2019-06-27 | — | — | US | disclosed |
| US-10167286-B2 | Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease | MITOKININ, INC. (US) | 2019-01-01 | — | — | US | disclosed |