SCHEMBL2059944

SCHEMBL2059944

NS(=O)(=O)NC(=O)CC(=O)NS(N)(=O)=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.44
CA2 P00918 10/20 0.44
CA9 Q16790 5/20 0.44
CA12 O43570 2/20 0.44
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA7 P43166 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
TSHR P16473 1/20 0.35
NT5E P21589 1/20 0.35
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7867744 0.85
SCHEMBL7345308 0.83
SCHEMBL8403828 0.83
SCHEMBL84246 0.79 CA12 (0.33) CA1CA2CA9CA12
SCHEMBL11198999 0.79 CA12 (0.33) CA1CA2CA9CA12FNTA
SCHEMBL11948539 0.79 CA1 (0.46) CA1CA2
SCHEMBL14345881 0.79 CTSD (0.52) CA1CA2CA9CA12ALDH1A1
SCHEMBL15925033 0.77 CA1 (0.47) CA1CA2CA9CA12LMNA
Hydrochloric Acid SCHEMBL10573949 0.77 CA12 (0.32) CA1CA2CA9CA12
SCHEMBL16181434 0.75 CA1 (0.49) CA1CA2CA9CA12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9381140-B2 Radically polymerisable dental material, cured product and usage KETTENBACH GMBH & CO. KG (DE) 2016-07-05 US claimed
US-20150231041-A1 Radically Polymerisable Dental Material, Cured Product and Usage KETTENBACH GMBH & CO. KG (DE) 2015-08-20 US claimed
US-6852775-B1 Polymerizable dental compositions 3M ESPE AG (DE) 2005-02-08 US claimed
EP-4377367-A1 COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, AN ALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLE AND METHOD 3M Innovative Properties Company (US) 2024-06-05 EP disclosed
US-11998417-B2 Process for producing a surface-modified dental article SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-06-04 US disclosed
US-20240084060-A1 COMPOSITION INCLUDING AN ACRYLIC MONOMER WITH A CARBOXYLIC ACID GROUP, AN ACRYLIC MONOMER WITH A HYDROXYL GROUP, AN ALKYL (METH)ACRYLATE MONOMER AND CROSSLINKER, AND RELATED ARTICLES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2024-03-14 US disclosed
US-20240076523-A1 FREE-RADICALLY POLYMERIZABLE CROSSLINKER, CURABLE COMPOSITION, AND ADHESIVE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2024-03-07 US disclosed
US-20240059940-A1 COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, A CYCLOALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2024-02-22 US disclosed
US-20230399463-A1 FREE-RADICALLY POLYMERIZABLE CROSSLINKER, CURABLE COMPOSITION, AND ADHESIVE THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2023-12-14 US disclosed
EP-4263640-A1 COMPOSITION INCLUDING AN ACRYLIC MONOMER WITH A CARBOXYLIC ACID GROUP, AN ACRYLIC MONOMER WITH A HYDROXYL GROUP, AN ALKYL (METH)ACRYLATE MONOMER AND CROSSLINKER, AND RELATED ARTICLES AND METHODS 3M Innovative Properties Company (US) 2023-10-25 EP disclosed
EP-4263737-A1 COMPOSITION INCLUDING MONOMER WITH A CARBOXYLIC ACID GROUP, MONOMER WITH A HYDROXYL GROUP, A CYCLOALKYL MONOMER, AND CROSSLINKER AND RELATED ARTICLES AND METHODS 3M Innovative Properties Company (US) 2023-10-25 EP disclosed
US-20040254260-A1 Use of branched polyacids in dental compounds 3M INNOVATIVE PROPERTIES COMPANY 2004-12-16 US disclosed
US-20030008967-A1 Radically curable urethane prepolymers and their use in dental materials 3M INNOVATIVE PROPERTIES COMPANY 2003-01-09 US disclosed
EP-1194110-A1 POLYMERIZABLE DENTAL SUBSTANCE ESPE Dental AG (DE) 2002-04-10 EP disclosed
WO-2000078271-A1 POLYMERIZABLE DENTAL SUBSTANCE 3M ESPE AG (DE) 2000-12-28 WO disclosed
US-5968998-A ADDITIONALLY CONTAINING SPECIFIED UNSATURATED ARYL COMPOUND TO LENGTHEN SETTING TIME ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) 1999-10-19 US disclosed
US-5824720-A DI OR MULTI(METH)ACRYLATES, INITIATORS, ACTIVATORS, FILLERS AND FLUORIDE COMPLEXES FOR DENTAL FILLING THERA PATENT GMBH & CO. KG GESELLSCHAFT FUR INDUSTRIELLE SCHUTZRECHTE (DE) 1998-10-20 US disclosed
US-5583164-A FREE RADICAL POLYMERIZATION; DELAY CURING ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) 1996-12-10 US disclosed
US-4544742-A PROMOTERS FOR DENTAL PEROXIDIC POLYMERIZATIONS SCHMITT WERNER (DE) 1985-10-01 US disclosed
US-4443587-A FOR ADDITION POLYMERS ABITZ, MORF, GRITSCHNEDER (DE) 1984-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150231041-A1 Radically Polymerisable Dental Material, Cured Product and Usage MMAB, MTCL3, TUBB4B CA1 45/4885CA2 856/4885CA9 791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.