SCHEMBL7345308

SCHEMBL7345308

NS(=O)(=O)NC(=O)CS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059944 0.83 CA1 (0.44)
SCHEMBL940077 0.78 TSHR (0.33)
SCHEMBL7867744 0.76
SCHEMBL8403828 0.74
SCHEMBL7739122 0.74
SCHEMBL11948539 0.70 CA1 (0.46)
SCHEMBL14345881 0.70 CTSD (0.52)
SCHEMBL84246 0.70 CA12 (0.33)
SCHEMBL11198999 0.70 CA12 (0.33)
SCHEMBL22203314 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020143011-A1 Tri-substituted phenyl derivatives and processes for their preparation CELLTECH THERAPEUTICS, LIMITED 2002-10-03 US disclosed
EP-0766670-B1 TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH R&D LTD (GB) 2002-03-27 EP disclosed
EP-0766673-B1 SUBSTITUTED OXIME DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH CHIROSCIENCE LTD (GB) 2002-01-30 EP disclosed
US-20010034450-A1 Tetra-substituted phenyl derivatives and processes for their preparation ALEXANDER RIKKI PETER (GB) 2001-10-25 US disclosed
US-6297264-B1 E.G., 4-(2-BENZYLOXY-2-(3-CYCLOPENTYLOXY-4-METHOXYPHENYL)ETHYL)PYRID INE; PHOSPHODIESTERASE INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 2001-10-02 US disclosed
US-6245774-B1 ANTIINFLAMMATORY AGENTS; BRONCHODILATOR AGENTS CELLTECH THERAPEUTICS LIMITED (GB) 2001-06-12 US disclosed
US-6197792-B1 PHOSPHODIESTERASE INHIBITOR CELLTECH THERAPEUTICS LIMITED (GB) 2001-03-06 US disclosed
US-6077854-A Tri-substituted phenyl derivatives and processes for their preparation CELLTECH THERAPEUTICS, LIMITED (GB) 2000-06-20 US disclosed
EP-0944599-A1 TRIARYLETHANES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1999-09-29 EP disclosed
US-5891896-A Tri-substituted phenyl derivatives useful as PDE IV inhibitors CELLTECH THERAPEUTICS LTD. (GB) 1999-04-06 US disclosed
EP-0770065-A1 TRI-SUBSTITUTED PHENYL DERIVATES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1997-05-02 EP disclosed
EP-0766669-A1 TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1997-04-09 EP disclosed
EP-0766671-A1 TETRA-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1997-04-09 EP disclosed
EP-0766670-A1 TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1997-04-09 EP disclosed
EP-0766673-A1 SUBSTITUTED OXIME DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1997-04-09 EP disclosed
WO-1996000215-A1 SUBSTITUTED OXIME DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1996-01-04 WO disclosed
WO-1995035281-A1 TRI-SUBSTITUTED PHENYL DERIVATES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1995-12-28 WO disclosed
WO-1995035284-A1 TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1995-12-28 WO disclosed
WO-1995035283-A1 TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1995-12-28 WO disclosed
WO-1995035285-A1 TETRA-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS CELLTECH THERAPEUTICS LIMITED (GB) 1995-12-28 WO disclosed