Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028791 | 0.91 | PSEN1 (0.37) | ALDH1A1CYP2C19GAAHSD17B10AMY1A | |
| SCHEMBL31303555 | 0.90 | GAA (0.36) | ALDH1A1CYP2C19GAAHSD17B10AMY1A | |
| SCHEMBL16028579 | 0.89 | TYR (0.41) | ALDH1A1CYP2C19GAAHSD17B10AMY1A | |
| SCHEMBL10604810 | 0.89 | PTPN2 (0.38) | ALDH1A1CYP2C19GAAHSD17B10MEN1 | |
| SCHEMBL31588190 | 0.88 | FUT7 (0.38) | ALDH1A1CYP2C19GAAHSD17B10AMY1A | |
| SCHEMBL3889264 | 0.88 | FUT7 (0.38) | ALDH1A1CYP2C19GAAHSD17B10AMY1A | |
| SCHEMBL10926819 | 0.88 | ALDH1A1 (0.35) | ALDH1A1CYP2C19GAAHSD17B10AMY1A | |
| SCHEMBL30561249 | 0.86 | LMNA (0.34) | ALDH1A1CYP2C19GAAHSD17B10AMY1A | |
| SCHEMBL30823619 | 0.86 | GAA (0.41) | ALDH1A1GAAHSD17B10AMY1AMEN1 | |
| SCHEMBL1180196 | 0.86 | GAA (0.41) | ALDH1A1GAAHSD17B10AMY1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515666-A | 2-Amino-quinoline derivatives | 博笛生物科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| CN-110637018-A | 2-amino-quinoline derivatives | 博笛生物科技有限公司 | 2019-12-31 | — | — | CN | disclosed |
| WO-2019000237-A1 | 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME CORP. (US) | 2019-01-03 | — | — | WO | disclosed |