Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380380 | 0.79 | EPHX2 (0.38) | — | |
| SCHEMBL2606813 | 0.79 | TSHR (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL4196480 | 0.79 | LMNA (0.48) | — | |
| SCHEMBL2606829 | 0.74 | CA12 (0.50) | — | |
| SCHEMBL20535845 | 0.71 | ABL1 (0.38) | — | |
| SCHEMBL4193315 | 0.71 | SMYD3 (0.39) | — | |
| SCHEMBL26922838 | 0.70 | GAA (0.33) | — | |
| SCHEMBL4193328 | 0.67 | LMNA (0.36) | — | |
| SCHEMBL9987692 | 0.67 | EPHX2 (0.33) | — | |
| SCHEMBL26923105 | 0.67 | KDM4E (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645516-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | Janssen Pharmaceutica NV (BE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019001420-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-03 | — | — | WO | disclosed |