Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600281 | 0.89 | KDM4E (0.56) | KDM4EPOLBPKMHSD17B10USP2 | |
| SCHEMBL2034454 | 0.75 | KDM4E (0.72) | KDM4EPOLBPKMHSD17B10USP2 | |
| SCHEMBL4734795 | 0.74 | KDM4E (1.00) | KDM4EPOLBPKMHSD17B10USP2 | |
| SCHEMBL25415240 | 0.71 | KDM4E (0.53) | KDM4EPOLBPKMHSD17B10ALDH1A1 | |
| SCHEMBL23489012 | 0.71 | KDM4E (0.66) | KDM4EPOLBPKMHSD17B10USP2 | |
| SCHEMBL28367230 | 0.70 | CA12 (0.35) | KDM4EPOLBHSD17B10ALDH1A1HPGD | |
| SCHEMBL29557419 | 0.70 | CA12 (0.35) | KDM4EPOLBHSD17B10ALDH1A1HPGD | |
| SCHEMBL30498915 | 0.69 | KDM4E (0.72) | KDM4EPOLBPKMHSD17B10USP2 | |
| SCHEMBL29025566 | 0.69 | PKM (0.57) | KDM4EPOLBPKMHSD17B10USP2 | |
| SCHEMBL28594907 | 0.69 | KDM4E (0.72) | KDM4EPOLBPKMHSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210079444-A1 | LABEL FREE DETECTION OF PROTEASE ACTIVITY | VIB VZW (BE) | 2021-03-18 | — | — | US | disclosed |
| EP-3645453-A1 | LABEL FREE DETECTION OF PROTEASE ACTIVITY | Universiteit Gent (BE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019002401-A1 | LABEL FREE DETECTION OF PROTEASE ACTIVITY | VIB VZW (BE) | 2019-01-03 | — | — | WO | disclosed |