Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20600282 | 0.89 | KDM4E (0.57) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL2034454 | 0.87 | KDM4E (0.72) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL25415240 | 0.82 | KDM4E (0.53) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL29025566 | 0.77 | PKM (0.57) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL23489254 | 0.75 | KDM4E (0.56) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL8911580 | 0.75 | PKM (0.58) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL642897 | 0.74 | KDM4E (0.54) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL18669122 | 0.74 | KDM4E (0.54) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL28270343 | 0.74 | KDM4E (0.54) | KDM4EPOLBPKMALDH1A1LCK | |
| SCHEMBL28594907 | 0.74 | KDM4E (0.72) | KDM4EPOLBPKMALDH1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210079444-A1 | LABEL FREE DETECTION OF PROTEASE ACTIVITY | VIB VZW (BE) | 2021-03-18 | — | — | US | disclosed |
| EP-3645453-A1 | LABEL FREE DETECTION OF PROTEASE ACTIVITY | Universiteit Gent (BE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019002401-A1 | LABEL FREE DETECTION OF PROTEASE ACTIVITY | VIB VZW (BE) | 2019-01-03 | — | — | WO | disclosed |