Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | MPC2 | O95563 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405431 | 1.00 | ACACB (0.34) | ACACBP4HTMCHRM2GRM5SIGMAR1 | |
| SCHEMBL28883583 | 0.79 | ALDH1A1 (0.35) | ACACBP4HTMCHRM2GRM5SIGMAR1 | |
| SCHEMBL19767100 | 0.75 | ACACB (0.37) | ACACBP4HTM | |
| SCHEMBL17992189 | 0.75 | KMT2A (0.41) | ACACBP4HTM | |
| SCHEMBL21982064 | 0.74 | P4HTM (0.32) | P4HTM | |
| SCHEMBL17992230 | 0.74 | BACE1 (0.38) | P4HTM | |
| SCHEMBL29120290 | 0.74 | MEN1 (0.33) | P4HTM | |
| SCHEMBL20474667 | 0.74 | ABL1 (0.37) | ACACBHRH3 | |
| SCHEMBL17992259 | 0.73 | MAOB (0.45) | — | |
| SCHEMBL17992227 | 0.73 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647308-B1 | HETEROARYL PYRIMIDINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO (JP) | 2023-05-31 | — | — | EP | disclosed |
| US-11427564-B2 | Heteroaryl pyrimidine compound and pest control agent | NIPPON SODA CO., LTD. (JP) | 2022-08-30 | — | — | US | disclosed |
| US-20200140414-A1 | HETEROARYL PYRIMIDINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2020-05-07 | — | — | US | disclosed |
| EP-3647308-A1 | HETEROARYL PYRIMIDINE COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2020-05-06 | — | — | EP | disclosed |
| CN-110831925-A | Heteroaryl pyrimidine compound and pest control agent | 日本曹达株式会社 | 2020-02-21 | — | — | CN | disclosed |
| WO-2019004082-A1 | HETEROARYL PYRIMIDINE COMPOUND AND PEST CONTROL AGENT | 日本曹達株式会社 | 2019-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427564-B2 | Heteroaryl pyrimidine compound and pest control agent | CTRL, C5, RER1 | ACACB 4297/4885P4HTM 4074/4885CHRM2 121/4885 |
| US-20200140414-A1 | HETEROARYL PYRIMIDINE COMPOUND AND PEST CONTROL AGENT | CTRL, C5, RER1 | ACACB 4297/4885P4HTM 4074/4885CHRM2 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.