Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076270 | 0.86 | NR1H4 (0.42) | PLA2G4AMCL1PPARGPPARDPPARA | |
| SCHEMBL14774587 | 0.83 | PTGER1 (0.58) | HTTPTGER1 | |
| SCHEMBL15076284 | 0.79 | PPARG (0.44) | PLA2G4APPARGPPARAHDAC3HDAC1 | |
| SCHEMBL15076216 | 0.78 | PTGER1 (0.46) | PLA2G4APPARGEPHX2NR1H4HDAC3 | |
| SCHEMBL20629016 | 0.78 | PLA2G4A (0.42) | PLA2G4APPARGPPARDPPARAEPHX2 | |
| SCHEMBL3351795 | 0.74 | MCL1 (0.61) | PLA2G4AMCL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14774570 | 0.73 | PTGER1 (0.56) | PPARGPTGER1 | |
| SCHEMBL29012864 | 0.72 | MCL1 (0.59) | PLA2G4AMCL1 | |
| SCHEMBL18783919 | 0.71 | PTGER1 (0.53) | LMNAHTTRAB9AALDH1A1PTGER1 | |
| SCHEMBL5981752 | 0.71 | MCL1 (0.57) | PLA2G4AMCL1EPHX2NR1H4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |