Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 13/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076284 | 0.94 | PPARG (0.44) | PLA2G4APPARGPPARANR1H2NR1H3 | |
| SCHEMBL15076270 | 0.88 | NR1H4 (0.42) | PLA2G4APPARGPPARAHDAC8HDAC6 | |
| SCHEMBL15076216 | 0.87 | PTGER1 (0.46) | PLA2G4APPARGHDAC8HDAC6HDAC3 | |
| SCHEMBL15057327 | 0.83 | PTGER1 (0.45) | PLA2G4APPARGHDAC8HDAC6HDAC3 | |
| SCHEMBL15057113 | 0.80 | PTGER1 (0.38) | — | |
| SCHEMBL15076247 | 0.79 | PPARG (0.47) | PLA2G4APPARG | |
| SCHEMBL15076267 | 0.79 | PPARG (0.41) | PPARGPPARA | |
| SCHEMBL20603549 | 0.78 | PLA2G4A (0.50) | PLA2G4APPARGPPARAHDAC8HDAC6 | |
| SCHEMBL15076241 | 0.78 | PLA2G4A (0.41) | PLA2G4A | |
| SCHEMBL20628900 | 0.76 | PTGER1 (0.37) | HDAC8HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |