SCHEMBL2060403

SCHEMBL2060403

COc1ccc(C(=O)c2ccccc2)c(O)c1C

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.77
KDM4E B2RXH2 4/20 0.77
HSD17B10 Q99714 3/20 0.77
MAPK1 P28482 3/20 0.77
ALOX15 P16050 2/20 0.77
LMNA P02545 7/20 0.61
HTT P42858 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
HPGD P15428 5/20 0.58
ALDH1A1 P00352 3/20 0.58
CYP3A4 P08684 2/20 0.58
RECQL P46063 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
CYP2C19 P33261 3/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
PGR P06401 1/20 0.53
SLC6A2 P23975 1/20 0.53
PDE4A P27815 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL613121 0.87 MAPT (0.66) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL93271 0.87 MAPT (1.00) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL29633691 0.86 NPC1 (0.62) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL2485347 0.86 NPC1 (0.62) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL10562648 0.84 MAPT (0.54) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL6444260 0.84 MAPT (0.77) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL29046142 0.83 MAPT (0.74) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL672605 0.83 MAPT (0.74) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL10549332 0.83 MAPT (0.74) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL10534410 0.83 MAPT (0.74) MAPTKDM4EHSD17B10MAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090061340-A1 HYDROXY BENZOPHENONE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US claimed
CN-114450026-A Sialic acid for use in the treatment of psoriasis 生命科学股份有限公司 2022-05-06 CN disclosed
CN-112189029-A Silicone polymers 莫门蒂夫性能材料股份有限公司 2021-01-05 CN disclosed
US-8148561-B2 Fatty ester mixture of 85% 2-ethylhexyl laurate/2-ethylhexyl myristate: emulsions; drug carriers, adjuvants; high-spreading oil, high softness, excellent personal (skin, hair) care properties, dermatological compatibility, little stickiness, no comedogenic potential; shampoo; creams; also papermaking COGNIS IP MANAGEMENT GMBH (DE) 2012-04-03 US disclosed
US-20080249172-A1 Cosmetic Oil Substances COGNIS IP MANAGEMENT GMBH (DE) 2008-10-09 US disclosed
US-7393817-B2 Tenside composition containing gemini tensides and co-amphiphiles and production and use thereof SASOL GERMANY GMBH (DE) 2008-07-01 US disclosed
US-20080051472-A1 Tenside composition containing gemini tensides and co-amphiphiles and production and use thereof SASOL GERMANY GMBH (DE) 2008-02-28 US disclosed
EP-1141187-B1 SURFACTANT COMPOSITION CONTAINING GEMINI SURFACTANTS AND CO-AMPHIPHILES, PRODUCTION AND USE THEREOF SASOL GERMANY GMBH (DE) 2005-03-02 EP disclosed
US-20040176266-A1 Tenside composition containing gemini tensides and co-amphiphiles and production and use thereof SASOL GERMANY GMBH (DE) 2004-09-09 US disclosed
EP-1131393-B1 TENSIDE COMPOSITION CONTAINING GEMINI TENSIDES AND USE THEREOF FOR CLEANING SKIN AND HAIR SASOL GERMANY GMBH (DE) 2004-08-11 EP disclosed
US-6710022-B1 EMULSIFIERS AND DISPERSANTS SASOL GERMANY GMBH (DE) 2004-03-23 US disclosed
WO-2003086420-A1 USE OF ACARBOSE AND THE DERIVATIVES THEREOF FOR THE TREATMENT AND PROPHYLAXIS OF DEGENERATIVE SKIN CONDITIONS BEIERSDORF AG (DE) 2003-10-23 WO disclosed
EP-1141187-A1 TENSIDE COMPOSITION CONTAINING GEMINI TENSIDES AND CO-AMPHIPHILES AND PRODUCTION AND USE THEREOF SASOL Germany GmbH (DE) 2001-10-10 EP disclosed
EP-1131393-A1 TENSIDE COMPOSITION CONTAINING GEMINI TENSIDES AND USE THEREOF FOR CLEANING SKIN AND HAIR SASOL Germany GmbH (DE) 2001-09-12 EP disclosed
WO-2001019943-A1 TENSIDE COMPOSITION CONTAINING GEMINI TENSIDES AND USE THEREOF FOR CLEANING SKIN AND HAIR SASOL GERMANY GMBH (DE) 2001-03-22 WO disclosed
WO-2001019945-A1 TENSIDE COMPOSITION CONTAINING GEMINI TENSIDES AND CO-AMPHIPHILES AND PRODUCTION AND USE THEREOF SASOL GERMANY GMBH (DE) 2001-03-22 WO disclosed
EP-1054945-A1 USE OF DETERGENT MIXTURES AS SOLUTIZERS Cognis Deutschland GmbH (DE) 2000-11-29 EP disclosed
WO-1999041341-A1 USE OF DETERGENT MIXTURES AS SOLUTIZERS COGNIS DEUTSCHLAND GMBH (DE) 1999-08-19 WO disclosed