SCHEMBL672605

SCHEMBL672605

COc1ccc(C(=O)c2ccccc2)c(O)c1Cc1c(OC)ccc(C(=O)c2ccccc2)c1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.74
KDM4E B2RXH2 4/20 0.74
HSD17B10 Q99714 3/20 0.74
MAPK1 P28482 3/20 0.74
ALOX15 P16050 2/20 0.74
LMNA P02545 7/20 0.60
HTT P42858 3/20 0.60
NPSR1 Q6W5P4 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HPGD P15428 5/20 0.56
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 2/20 0.56
RECQL P46063 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP2C19 P33261 2/20 0.51
PGR P06401 1/20 0.51
SLC6A2 P23975 1/20 0.51
PDE4A P27815 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13121658 0.91 MAPT (0.70) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL11443544 0.86 MAPT (0.63) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL11524206 0.86 MAPT (0.61) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL93271 0.85 MAPT (1.00) MAPTKDM4EHSD17B10MAPK1ALOX15
Fumaric Acid SCHEMBL11220538 0.85 MAPT (0.62) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL11431486 0.84 MAPT (0.60) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL2060403 0.83 MAPT (0.77) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL6444260 0.83 MAPT (0.77) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL29046142 0.81 MAPT (0.74) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL10549332 0.81 MAPT (0.74) MAPTKDM4EHSD17B10MAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630758-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-10-07 EP claimed
US-5466655-A STORAGE STABILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1995-11-14 US claimed
EP-0630758-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1994-12-28 EP claimed
EP-3749715-B1 POLYMER COMPOSITION FOR ROTATIONAL MOULDING MATRIX POLYMERS LTD (GB) 2022-04-27 EP disclosed
EP-3749715-A1 POLYMER COMPOSITION FOR ROTATIONAL MOULDING Matrix Polymers Limited (GB) 2020-12-16 EP disclosed
WO-2019155213-A1 POLYMER COMPOSITION FOR ROTATIONAL MOULDING MATRIX POLYMERS LIMITED (GB) 2019-08-15 WO disclosed
EP-2473265-A1 MASTERBATCH COMPOSITION HAVING A HIGH POLYMER PROCESSING AID Carolina Color Corporation (US) 2012-07-11 EP disclosed
US-7968632-B2 Polycarbonate resin composition and process for producing thereof MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2011-06-28 US disclosed
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
WO-2011028206-A1 MASTERBATCH COMPOSITION HAVING A HIGH POLYMER PROCESSING AID CAROLINA COLOR CORPOARTION (US) 2011-03-10 WO disclosed
EP-0630758-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-10-07 EP disclosed
EP-0813568-A1 HIGHLY LIGHT-STABLE POLYAMIDE COMPOSITION NYLTECH FRANCE (FR) 1997-12-29 EP disclosed
WO-1996028503-A1 HIGHLY LIGHT-STABLE POLYAMIDE COMPOSITION NYLTECH FRANCE (FR) 1996-09-19 WO disclosed
US-5466655-A STORAGE STABILITY MITSUBISHI PAPER MILLS LIMITED (JP) 1995-11-14 US disclosed
EP-0630758-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1994-12-28 EP disclosed
EP-0610155-A1 Stabilized polyamide compositions CIBA-GEIGY AG (CH) 1994-08-10 EP disclosed
US-4189409-A LIGHT STABILIZERS, IN THE PRESENCE OF AN ACID CATALYST ARGUS CHEMICAL CORPORATION (US) 1980-02-19 US disclosed
US-4186151-A Process for preparing a 5,5'-methylenebis(2-hydroxy-4-alkoxybenzophenone) ARGUS CHEMICAL CORPORATION (US) 1980-01-29 US disclosed
US-4169089-A PHOTOSTABILIZERS FOR POLYMERS ARGUS CHEMICAL CORPORATION (US) 1979-09-25 US disclosed