Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 17/20 | 0.83 |
| ▸ | CASP7 | P55210 | 10/20 | 0.83 |
| ▸ | CASP1 | P29466 | 5/20 | 0.70 |
| ▸ | CASP9 | P55211 | 4/20 | 0.70 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967979 | 1.00 | CASP3 (0.83) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL12829828 | 0.96 | CASP3 (0.76) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL18782019 | 0.95 | CASP3 (0.74) | CASP3CASP7CASP1CASP9CTSL | |
| SCHEMBL7970356 | 0.94 | CASP3 (0.82) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL19015899 | 0.94 | CASP3 (0.82) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL7970335 | 0.92 | CASP3 (0.83) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL20609297 | 0.92 | CASP3 (0.83) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL19015959 | 0.92 | CASP3 (0.83) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL19015958 | 0.92 | CASP3 (0.83) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL16377056 | 0.91 | CASP3 (1.00) | CASP3CASP7CASP1CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167313-B2 | Selective caspase inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2019-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167313-B2 | Selective caspase inhibitors and uses thereof | CASP1, CASP3, CASP5 | CASP3 2/4885CASP7 7/4885CASP1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.