Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967833 | 0.84 | PTPRA (0.53) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13272888 | 0.81 | GRIN2D (0.50) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7566490 | 0.81 | GRIN2D (0.50) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL23791946 | 0.80 | ALDH1A1 (0.46) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrazine SCHEMBL2567074 | 0.80 | HRH1 (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL20128507 | 0.79 | GRIN2D (0.52) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20153445 | 0.79 | GRIN2D (0.52) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL23765410 | 0.79 | GRIN2D (0.52) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2352782 | 0.78 | GRIN2D (0.55) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL104860 | 0.78 | GRIN2D (0.55) | PTPRAGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10458995-B2 | Combinatorial synthesis and biomarker development | TEN30 BIOSCIENCES, INC. | 2019-10-29 | — | — | US | disclosed |
| US-20190113521-A1 | COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT | TEN30 BIOSCIENCES, INC. | 2019-04-18 | — | — | US | disclosed |
| US-10167270-B2 | Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity | NORTHWESTERN UNIVERSITY (US) | 2019-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190113521-A1 | COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT | APP, PSEN2, PSEN1 | PTPRA 2648/4885GRIN2D 219/4885GRIN3B 134/4885 |
| US-10167270-B2 | Substituted quinazoline compounds and uses thereof for modulating glucocerebrosidase activity | GBA1, GAA, GBA2 | PTPRA 3199/4885GRIN2D 1338/4885GRIN3B 551/4885 |
| US-10458995-B2 | Combinatorial synthesis and biomarker development | APP, PSEN2, PSEN1 | PTPRA 2667/4885GRIN2D 227/4885GRIN3B 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.