Hydrazine

Hydrazine

SCHEMBL2567074

CCC(CCc1ccccn1)C(C)C.NN

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.49
CYP1A2 P05177 3/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP2C19 P33261 1/20 0.46
HRH3 Q9Y5N1 1/20 0.45
LMNA P02545 2/20 0.44
TAAR1 Q96RJ0 1/20 0.44
ALOX15 P16050 1/20 0.44
POLB P06746 2/20 0.40
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TSHR P16473 2/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20609338 0.80 PTPRA (0.50) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL18098078 0.80 CYP1A2 (0.51) HRH1CYP1A2ALDH1A1CYP2C19HRH3
Hydrochloric Acid SCHEMBL30593945 0.78 ALDH1A1 (0.51) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL21510401 0.78 HRH1 (0.53) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL19079581 0.78 HRH1 (0.53) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL10771160 0.78 HRH1 (0.57) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL6938906 0.78 HRH1 (0.57) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL19865660 0.78 CYP1A2 (0.53) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL30201139 0.77 CYP1A2 (0.61) HRH1CYP1A2ALDH1A1CYP2C19HRH3
SCHEMBL574013 0.77 CYP1A2 (0.61) HRH1CYP1A2ALDH1A1CYP2C19HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2382274-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF Coatings GmbH (DE) 2011-11-02 EP disclosed
WO-2010077404-A1 PYRIDINE GROUP-CONTAINING ELECTROCOAT RESIN BASF COATINGS GMBH (US) 2010-07-08 WO disclosed