Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 8/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141362 | 0.80 | TOP2A (0.50) | TOP2AMAOAMAOBMEN1KMT2A | |
| SCHEMBL20609332 | 0.78 | ELANE (0.38) | TOP2AMAOAMAOBELANECTSG | |
| SCHEMBL16870455 | 0.75 | MAOA (0.47) | MAOAMAOBELANECTSGALDH1A1 | |
| SCHEMBL18213641 | 0.75 | MAOA (0.41) | TOP2AMAOAMAOBELANECTSG | |
| SCHEMBL16870532 | 0.72 | MAOA (0.45) | MAOAMAOBELANECTSGALDH1A1 | |
| SCHEMBL16870423 | 0.72 | MAOA (0.45) | MAOAMAOBELANECTSGALDH1A1 | |
| SCHEMBL18205608 | 0.72 | MAOA (0.45) | MAOAMAOBELANECTSGALDH1A1 | |
| SCHEMBL16870512 | 0.72 | MAOA (0.45) | MAOAMAOBELANECTSGALDH1A1 | |
| SCHEMBL18205655 | 0.72 | MAOA (0.45) | MAOAMAOBELANECTSGALDH1A1 | |
| Mansonone E SCHEMBL30656080 | 0.70 | TOP2A (1.00) | TOP2AMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167269-B2 | Cockroach attraction-aggregation substance, cockroach aggregation attractant and cockroach controlling agent | KYOTO UNIVERSITY (JP) | 2019-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167269-B2 | Cockroach attraction-aggregation substance, cockroach aggregation attractant and cockroach controlling agent | ACHE, STOM, NAPA | TOP2A 4875/4885MAOA 2164/4885MAOB 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.