Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17171914 | 0.89 | CYP3A4 (0.46) | CYP3A4CYP2C9CYP2C19CYP19A1CYP2D6 | |
| SCHEMBL17157474 | 0.88 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19CYP19A1CYP2D6 | |
| SCHEMBL17157392 | 0.87 | NPY5R (0.44) | CYP3A4CYP2C9CYP2C19CYP19A1CYP2D6 | |
| SCHEMBL17172338 | 0.85 | CYP2C9 (0.43) | CYP3A4CYP2C9CYP2C19CYP19A1CYP2D6 | |
| SCHEMBL17172223 | 0.83 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP2C19CYP19A1CYP2D6 | |
| SCHEMBL17195958 | 0.81 | KIF11 (0.57) | CYP3A4CYP19A1CYP3A5KIF11GPR55 | |
| SCHEMBL17171925 | 0.81 | CYP19A1 (0.39) | CYP3A4CYP2C9CYP2C19CYP19A1CYP2D6 | |
| SCHEMBL17172278 | 0.79 | NPY5R (0.41) | CYP3A4CYP2C9CYP2C19CYP19A1CYP2D6 | |
| SCHEMBL17157462 | 0.77 | L3MBTL1 (0.41) | CYP3A4CYP2C9CYP2C19CYP1A2DGAT1 | |
| SCHEMBL17172272 | 0.77 | ALOX5AP (0.43) | CYP3A4CYP2C9CYP2C19CYP3A5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | GPX1, POR, MGAM | CYP3A4 89/4885CYP2C9 68/4885CYP2C19 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.