Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20597505 | 0.77 | PIM2 (0.32) | PARP1 | |
| SCHEMBL30116183 | 0.77 | PIM2 (0.32) | PARP1 | |
| SCHEMBL20612908 | 0.76 | MGLL (0.41) | FFAR4 | |
| Hydrochloric Acid SCHEMBL22694634 | 0.76 | PIM2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL30116244 | 0.76 | PIM2 (0.32) | — | |
| SCHEMBL20613066 | 0.74 | FFAR4 (0.42) | FFAR4 | |
| SCHEMBL20612923 | 0.71 | DRD4 (0.50) | HTR2CHTR2BFFAR4 | |
| SCHEMBL25970060 | 0.71 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL20613106 | 0.70 | FFAR4 (0.40) | FFAR4 | |
| SCHEMBL20613099 | 0.70 | FFAR4 (0.42) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-A1 | PIPERIDINE DERIVATIVE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2019-01-02 | — | — | EP | disclosed |