SCHEMBL20613699

SCHEMBL20613699

CC(I)(c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.68
ESR2 Q92731 10/20 0.68
CYP3A4 P08684 3/20 0.68
ALDH1A1 P00352 3/20 0.68
LMNA P02545 1/20 0.52
TYR P14679 1/20 0.52
AR P10275 1/20 0.52
HPGD P15428 1/20 0.52
TSHR P16473 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR6 P50406 1/20 0.52
ESRRG P62508 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
GLA P06280 1/20 0.43
CA3 P07451 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7212060 0.91 ESR1 (0.62) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL1921744 0.85 KCNN4 (0.50) ESR1ESR2CYP3A4ALDH1A1TSHR
SCHEMBL4310025 0.81 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL8031149 0.81 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL9353524 0.81 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL14597247 0.81 ESR1 (0.74) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL51117 0.81 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL27277 0.81 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL16568667 0.79 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1LMNA
Phenol SCHEMBL5691556 0.79 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2921515-B1 PRODUCTION METHOD FOR AROMATIC POLYCARBONATE RESIN HAVING INCREASED MOLECULAR WEIGHT MITSUBISHI GAS CHEMICAL CO (JP) 2019-01-02 EP disclosed