SCHEMBL8031149

SCHEMBL8031149

CC(c1ccccc1)(c1ccccc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 1.00
ESR2 Q92731 10/20 1.00
CYP3A4 P08684 3/20 0.74
ALDH1A1 P00352 3/20 0.74
LMNA P02545 1/20 0.56
TYR P14679 1/20 0.56
AR P10275 1/20 0.56
HPGD P15428 1/20 0.56
TSHR P16473 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
HTR6 P50406 1/20 0.56
ESRRG P62508 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27277 1.00 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1LMNA
Phenol SCHEMBL29851136 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1LMNA
Methane SCHEMBL16667289 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1LMNA
Phenol SCHEMBL8987629 0.95 ESR1 (0.91) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL23059478 0.93 ESR1 (0.87) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL5861516 0.93 ESR1 (0.87) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL3660292 0.93 ESR1 (0.87) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL22336095 0.93 ESR1 (0.87) ESR1ESR2CYP3A4ALDH1A1LMNA
Bicarbonate SCHEMBL19723102 0.93 ESR1 (0.87) ESR1ESR2CYP3A4ALDH1A1LMNA
Bisphenol A SCHEMBL7237612 0.93 ESR1 (0.87) ESR1ESR2CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US claimed
CN-110072910-B Color reducing polycarbonate compositions, methods of manufacture, and articles thereof 沙特基础工业全球技术有限公司 2021-08-13 CN disclosed
CN-107001689-B Suspension polymerization compositions, methods and uses thereof 纳米-尺寸科技有限公司 2021-02-09 CN disclosed
CN-109535396-A The 4th subgroup metal complex of porous organic polymer ligand and purposes 吉林大学 2019-03-29 CN disclosed
US-20170037243-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-09 US disclosed
US-20170029618-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-02 US disclosed
US-20170022362-A1 HIGH HEAT POLYCARBONATE COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-01-26 US disclosed
CN-105264016-A Reinforcing agent for polycarbonate resin, polycarbonate resin composition, and molded article MITSUBISHI CHEM CORP 2016-01-20 CN disclosed
WO-2015021092-A1 POLYCONJUGATES FOR DELIVERY OF RNAI TRIGGERS TO TUMOR CELLS IN VIVO ARROWHEAD RESEARCH CORPORATION (US) 2015-02-12 WO disclosed
CN-1109073-C Aromatic polycarbonate resin composition GEN ELECTRIC (US) 2003-05-21 CN disclosed
WO-1999001495-A1 METHOD FOR PRODUCING BRANCHED POLYCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 1999-01-14 WO disclosed
US-5399455-A Electrophotographic toner composition and image fixing process FUJI XEROX CO., LTD. (JP) 1995-03-21 US disclosed
US-4891297-A STORAGE STABILITY, HIGH COLOR DENSITY FUJI PHOTO FILM CO.,LTD. (JP) 1990-01-02 US disclosed
EP-0323887-A2 Heat-sensitive diazo recording materials FUJI PHOTO FILM CO., LTD. (JP) 1989-07-12 EP disclosed
US-4824721-A CAPSULES OF OIL SOLUBLE DYES WHICH SWELL AND RELEASE DYE UPON HEATING FUJI PHOTO FILM CO., LTD. (JP) 1989-04-25 US disclosed
US-4758495-A Diazo microcapsule recording material prepared using ion exchange treatment FUJI PHOTO FILM CO., LTD. (JP) 1988-07-19 US disclosed
US-4749679-A Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1988-06-07 US disclosed
US-4682194-A MICROCAPSULES CONTAINING LEUCO DYE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed
US-4219219-A Developers for pressure-sensitive recording and developing sheets containing them FUJI PHOTO FILM CO., LTD. (JP) 1980-08-26 US disclosed