SCHEMBL206138

SCHEMBL206138

CCC([O])Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.50
TAAR1 Q96RJ0 5/20 0.48
SIGMAR1 Q99720 4/20 0.48
SLC6A2 P23975 2/20 0.48
MAOA P21397 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48
ADORA1 P30542 1/20 0.48
ALPL P05186 1/20 0.47
POLB P06746 1/20 0.47
ALPG P10696 1/20 0.47
CYP1A2 P05177 1/20 0.46
EPHX1 P07099 1/20 0.46
TP53 P04637 1/20 0.46
SLC18A2 Q05940 1/20 0.45
CYP2D6 P10635 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1833632 0.85 EPHX1 (0.55) TRPA1TAAR1SIGMAR1SLC6A2MAOA
SCHEMBL9641434 0.82 SIGMAR1 (0.46) TRPA1TAAR1SIGMAR1SLC6A2MAOA
SCHEMBL5903351 0.79 CNR2 (0.47) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL1678091 0.77 TSHR (0.46) POLBCYP1A2TP53MEN1KMT2A
SCHEMBL6204860 0.77 TSHR (0.47) TRPA1TAAR1SIGMAR1SLC6A2MAOA
SCHEMBL1975377 0.76 TRPA1 (0.50) TRPA1TAAR1SIGMAR1SLC6A2MAOA
SCHEMBL2243355 0.76 TRPA1 (0.50) TRPA1TAAR1SIGMAR1SLC6A2MAOA
SCHEMBL4337931 0.76 TRPA1 (0.54) TRPA1ALPLPOLBALPGCYP1A2
SCHEMBL9407376 0.76 EPHX1 (0.52) TAAR1SIGMAR1SLC6A2MAOASLC6A4
SCHEMBL10821452 0.76 CSNK1E (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024129637-A1 DECREASING TRIBOELECTRIC CHARGING OF, AND/OR REACTOR FOULING BY, POLYOLEFIN PARTICLES UNIVATION TECHNOLOGIES, LLC (US) 2024-06-20 WO disclosed
US-11384164-B2 Methods and systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC (US) 2022-07-12 US disclosed
EP-3283532-B1 METHODS AND SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECH LLC (US) 2022-05-18 EP disclosed
US-11117991-B2 Methods for operating a polymerization reactor UNIVATION TECHNOLOGIES, LLC (US) 2021-09-14 US disclosed
CN-107531839-B Method for operating a polymerization reactor 尤尼威蒂恩技术有限责任公司 2021-05-25 CN disclosed
CN-107531827-B Process and system for olefin polymerization 尤尼威蒂恩技术有限责任公司 2021-04-23 CN disclosed
US-20200299418-A1 METHODS AND SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2020-09-24 US disclosed
US-10711072-B2 Methods and systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC (US) 2020-07-14 US disclosed
EP-2750797-B1 METHODS OF PREPARING A CATALYST SYSTEM UNIVATION TECH LLC (US) 2020-04-01 EP disclosed
EP-3286228-B1 METHODS FOR OPERATING A POLYMERIZATION REACTOR UNIVATION TECH LLC (US) 2020-03-18 EP disclosed
WO-1993024456-A1 SUBSTITUTED ISOINDOLONES BASF AKTIENGESELLSCHAFT (DE) 1993-12-09 WO disclosed
WO-1993022280-A1 SUBSTITUTED CYCLOHEXENE-1,2-BICARBOXYLIC ACID DERIVATIVES AND RAW MATERIALS FOR PRODUCING THEM BASF AKTIENGESELLSCHAFT (DE) 1993-11-11 WO disclosed
CN-1075716-A The drying of plant materials part and the method that comes off BASF AG (DE) 1993-09-01 CN disclosed
WO-1993011669-A1 USE OF 3-PHENYLURACIL DERIVATIVES FOR THE DESICCATION AND ABSCISSION OF PLANT PARTS BASF AKTIENGESELLSCHAFT (DE) 1993-06-24 WO disclosed
WO-1993005053-A1 PROCESS FOR PRODUCING α-CHLOR-METHYLEN-TRIORGANYLPHOSPHORANE DERIVATES BASF AKTIENGESELLSCHAFT (DE) 1993-03-18 WO disclosed
EP-0425134-A1 Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-05-02 EP disclosed
EP-0369810-A2 PAF antagonists as anti-hyperendothelinemia agents Takeda Chemical Industries, Ltd. (JP) 1990-05-23 EP disclosed
US-4713381-A ANTICOAGULANTS, ANALGESICS, ANTIINFLAMMATORY AGENT YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1987-12-15 US disclosed
EP-0226641-A1 OXODIAZINE COMPOUNDS. YOSHITOMI PHARMACEUTICAL (JP) 1987-07-01 EP disclosed
WO-1986007059-A2 OXODIAZINE COMPOUNDS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1986-12-04 WO disclosed