Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20593176 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALOX15HTTALDH1A1LMNA | |
| SCHEMBL20593177 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2ALOX15HTTALDH1A1LMNA | |
| SCHEMBL20593175 | 0.74 | LMNA (0.36) | SMN1; SMN2HTTALDH1A1LMNAIDO1 | |
| SCHEMBL6442643 | 0.67 | LMNA (0.37) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL6442639 | 0.67 | LMNA (0.37) | SMN1; SMN2LMNACA12CA1CA2 | |
| SCHEMBL2545589 | 0.67 | CA1 (0.38) | SMN1; SMN2ALOX15HTTALDH1A1CA1 | |
| SCHEMBL2545587 | 0.67 | CA1 (0.38) | SMN1; SMN2ALOX15HTTALDH1A1CA1 | |
| SCHEMBL29018914 | 0.67 | IDO1 (0.39) | HTTALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL17066150 | 0.65 | ALDH1A1 (0.40) | ALDH1A1LMNAIDO1 | |
| SCHEMBL20593188 | 0.65 | LMNA (0.42) | ALDH1A1LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421456-A1 | NEW ROUTE OF SYNTHESIS FOR OPICAPONE | AZAD Pharmaceutical Ingredients AG (CH) | 2019-01-02 | — | — | EP | disclosed |