Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20614927 | 0.90 | KDM4E (0.38) | MEN1KMT2AKDM4ESMARCA4CYP3A4 | |
| SCHEMBL20614794 | 0.83 | KDM4E (0.35) | MEN1KMT2AKDM4ESMARCA4PBRM1 | |
| SCHEMBL19151284 | 0.81 | MEN1 (0.51) | MEN1KMT2AKDM4ESMARCA4MAPT | |
| SCHEMBL7241088 | 0.76 | KMT2A (0.49) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL7241092 | 0.76 | KMT2A (0.49) | MEN1KMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL20614928 | 0.75 | KDM4E (0.35) | MEN1KMT2AKDM4ESMARCA4CYP3A4 | |
| SCHEMBL20614685 | 0.74 | SMARCA4 (0.38) | MEN1KMT2AKDM4ESMARCA4PBRM1 | |
| SCHEMBL19150902 | 0.72 | ALDH1A1 (0.36) | MEN1KMT2AKDM4ESMARCA4PBRM1 | |
| SCHEMBL20614744 | 0.70 | PLK1 (0.39) | MEN1KMT2ACYP3A4MAPTCYP2D6 | |
| SCHEMBL20614746 | 0.68 | CDC25B (0.35) | MEN1KMT2AKDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006291-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |