Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20614933 | 0.87 | PLK1 (0.39) | PLK1CSNK2A1PLK3BRD4BRD2 | |
| SCHEMBL20614893 | 0.77 | CHRM2 (0.33) | PLK1CSNK2A1PLK3ALDH1A1MEN1 | |
| SCHEMBL29960722 | 0.76 | MEN1 (0.50) | BRD4BRD2ALDH1A1MEN1GAA | |
| SCHEMBL14408830 | 0.76 | MEN1 (0.50) | BRD4BRD2ALDH1A1MEN1GAA | |
| SCHEMBL16998410 | 0.76 | SIGMAR1 (0.48) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL22367438 | 0.74 | PARP1 (0.40) | CYP3A4PKN1PKN2PARP1 | |
| SCHEMBL7977375 | 0.73 | CHRM2 (0.49) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL31555114 | 0.73 | CHRM2 (0.49) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL22674242 | 0.71 | SIGMAR1 (0.52) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL14746122 | 0.71 | NOTUM (0.42) | BRD4BRD2ALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006291-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |