Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906838 | 0.84 | GABRR1 (0.31) | PLGPLATLMNAGABRR1ACE | |
| SCHEMBL2060712 | 0.78 | — | — | |
| SCHEMBL11664391 | 0.71 | LMNA (0.65) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL6869149 | 0.69 | GABRR1 (0.37) | PLGPLATLMNAGABRR1ACE | |
| SCHEMBL14947098 | 0.68 | ANPEP (0.47) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL5008463 | 0.64 | GABRR1 (0.38) | PLGPLATLMNAANPEPGABRR1 | |
| SCHEMBL6911327 | 0.63 | LMNA (0.60) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL28958476 | 0.63 | LMNA (0.43) | PLGPLATLMNAGABRR1 | |
| SCHEMBL28176551 | 0.63 | PLG (0.48) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL27558911 | 0.63 | PLG (0.48) | PLGPLATLMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148422-B2 | Sulfonamides as TRPM8 modulators | JANSSEN PHARMACEUTICA, NV (BE) | 2012-04-03 | — | — | US | disclosed |