Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.37 |
| ▸ | HTR2B | P41595 | 10/20 | 0.37 |
| ▸ | HTR2A | P28223 | 9/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARG | P13631 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20615913 | 1.00 | HTR2C (0.37) | HTR2CHTR2BHTR2AMMP13LMNA | |
| Trifluoroacetic Acid SCHEMBL23898105 | 0.94 | HTR2C (0.35) | HTR2CHTR2BHTR2AMMP13LMNA | |
| SCHEMBL20615980 | 0.88 | LMNA (0.35) | HTR2CHTR2BHTR2ALMNAMAPK1 | |
| SCHEMBL20616178 | 0.86 | HTR2C (0.38) | HTR2CHTR2BHTR2ALMNA | |
| Hydrochloric Acid SCHEMBL23898116 | 0.85 | HTR2C (0.37) | HTR2CHTR2BHTR2ALMNA | |
| Hydrochloric Acid SCHEMBL21838834 | 0.85 | HTR2C (0.37) | HTR2CHTR2BHTR2ALMNA | |
| SCHEMBL20615714 | 0.85 | SCN9A (0.35) | HTR2CHTR2BHTR2A | |
| SCHEMBL20615716 | 0.85 | SCN9A (0.35) | HTR2CHTR2BHTR2A | |
| SCHEMBL20616273 | 0.84 | HTR2C (0.33) | HTR2CHTR2BHTR2A | |
| SCHEMBL21838861 | 0.83 | HTR2C (0.34) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019001396-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-01-03 | — | — | WO | disclosed |