Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.35 |
| ▸ | HTR2B | P41595 | 9/20 | 0.35 |
| ▸ | HTR2A | P28223 | 9/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 3/20 | 0.30 |
| ▸ | RARG | P13631 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20615913 | 0.94 | HTR2C (0.37) | HTR2CHTR2BHTR2AMMP13LMNA | |
| SCHEMBL20615914 | 0.94 | HTR2C (0.37) | HTR2CHTR2BHTR2AMMP13LMNA | |
| SCHEMBL21838861 | 0.86 | HTR2C (0.34) | HTR2CHTR2BHTR2ASCN9A | |
| Trifluoroacetic Acid SCHEMBL31655669 | 0.83 | F10 (0.39) | HTR2CHTR2BHTR2A | |
| SCHEMBL20615980 | 0.82 | LMNA (0.35) | HTR2CHTR2BHTR2ALMNAMAPK1 | |
| SCHEMBL20616273 | 0.81 | HTR2C (0.33) | HTR2CHTR2BHTR2ASCN9A | |
| SCHEMBL20616178 | 0.81 | HTR2C (0.38) | HTR2CHTR2BHTR2ALMNA | |
| Hydrochloric Acid SCHEMBL21838971 | 0.80 | DPP4 (0.33) | HTR2C | |
| Hydrochloric Acid SCHEMBL23898124 | 0.80 | DPP4 (0.33) | HTR2C | |
| Hydrochloric Acid SCHEMBL23898116 | 0.80 | HTR2C (0.37) | HTR2CHTR2BHTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142527-B2 | Dihydropyrimidine compounds and uses thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142527-B2 | Dihydropyrimidine compounds and uses thereof in medicine | DPYD, SLC10A1, DHODH | HTR2C 3558/4885HTR2B 3462/4885HTR2A 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.