Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12248461 | 0.69 | S1PR1 (0.64) | KMT2AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL18559194 | 0.69 | TSHR (0.81) | KDM4EGAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL14970814 | 0.67 | SMN1; SMN2 (0.71) | KMT2AGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL18559294 | 0.66 | TSHR (0.88) | KDM4EGAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL14359497 | 0.65 | ATM (0.73) | KMT2AKDM4EGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13753637 | 0.65 | ATM (0.64) | KMT2AALDH1A1SMN1; SMN2HPGDLMNA | |
| SCHEMBL1754131 | 0.65 | ATM (0.67) | KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL30522592 | 0.65 | ATM (0.67) | KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL22019391 | 0.64 | ALDH1A1 (0.74) | KMT2AKDM4EGAATSHRALDH1A1 | |
| SCHEMBL4197540 | 0.64 | ALDH1A1 (0.61) | KMT2AKDM4EGAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019002624-A1 | MEDICAMENTS FOR TREATING INFLAMMATORY BOWEL DISEASES | KLEUSER, BURKHARD (DE) | 2019-01-03 | — | — | WO | disclosed |