Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753638 | 0.85 | HPGD (0.64) | ATMPARP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13753654 | 0.85 | SMN1; SMN2 (0.57) | ATMPARP1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13753786 | 0.84 | HPGD (0.65) | SMN1; SMN2ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL13753789 | 0.84 | HPGD (0.51) | ATMTAS1R3TAS1R1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13753787 | 0.83 | TAS1R3 (0.61) | TAS1R3TAS1R1PARP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4796548 | 0.82 | ATM (0.63) | ATMTAS1R3TAS1R1HDAC8HDAC6 | |
| SCHEMBL13753648 | 0.82 | NPSR1 (0.65) | TAS1R3TAS1R1ALDH1A1LMNACTSL | |
| SCHEMBL13753576 | 0.81 | ATM (0.73) | ATMTAS1R3TAS1R1HDAC8HDAC6 | |
| SCHEMBL14359497 | 0.81 | ATM (0.73) | ATMTAS1R3TAS1R1HDAC8HDAC6 | |
| SCHEMBL13753788 | 0.81 | ALDH1A1 (0.59) | TAS1R3TAS1R1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |