SCHEMBL20617079

SCHEMBL20617079

N#Cc1cc(-c2cc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccccc6)c5c43)c(C#N)c(-n3c4ccccc4c4ccc5c6ccccc6n(-c6ccccc6)c5c43)c2)cc(C(F)(F)F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.40
RXRG P48443 1/20 0.40
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PGR P06401 1/20 0.36
KIF11 P52732 1/20 0.34
TAS2R14 Q9NYV8 1/20 0.34
PDPK1 O15530 1/20 0.33
KDR P35968 2/20 0.33
CTSK P43235 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
XDH P47989 1/20 0.32
DRD2 P14416 1/20 0.32
DRD3 P35462 1/20 0.32
MAT2A P31153 1/20 0.31
REN P00797 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19903684 0.95 KDM4E (0.41) RXRARXRGKDM4EATML3MBTL1
SCHEMBL20617097 0.92 RXRA (0.38) RXRARXRGKDM4EATML3MBTL1
SCHEMBL21414293 0.90 KDM4E (0.45) KDM4EATML3MBTL1PGRKDR
SCHEMBL19912398 0.90 KDM4E (0.37) RXRARXRGKDM4EATML3MBTL1
SCHEMBL20617130 0.89 RXRA (0.43) RXRARXRGKDM4EATML3MBTL1
SCHEMBL20617084 0.88 KIF11 (0.43) RXRARXRGKDM4EL3MBTL1KIF11
SCHEMBL22564579 0.88 RXRA (0.38) RXRARXRGKDM4EATML3MBTL1
SCHEMBL22822431 0.87 RXRA (0.39) RXRARXRGKDM4EATML3MBTL1
SCHEMBL22564490 0.87 RXRA (0.39) RXRARXRGKDM4EATML3MBTL1
SCHEMBL20617065 0.86 KIF11 (0.44) RXRARXRGKIF11TAS2R14PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021473-B2 Organic molecules for use in organic optoelectronic devices CYNORA GMBH (DE) 2021-06-01 US disclosed
US-20200399256-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-24 US disclosed
EP-3642302-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed
WO-2019001838-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11021473-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 RXRA 3552/4885RXRG 3138/4885KDM4E 4274/4885
US-20200399256-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 RXRA 3876/4885RXRG 3543/4885KDM4E 3454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.