Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884144 | 0.73 | TSHR (0.41) | TSHR | |
| SCHEMBL6745199 | 0.71 | — | — | |
| SCHEMBL5275675 | 0.69 | MAPT (0.31) | — | |
| SCHEMBL9665870 | 0.68 | MEN1 (0.33) | KMT2AMEN1 | |
| SCHEMBL12344045 | 0.67 | — | — | |
| SCHEMBL6565787 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL960244 | 0.64 | GAA (0.32) | — | |
| SCHEMBL6760731 | 0.63 | BRD9 (0.41) | GLAKMT2ABRD9BRD7MEN1 | |
| SCHEMBL21451063 | 0.63 | TSHR (0.31) | TSHR | |
| SCHEMBL17132892 | 0.63 | HTR2C (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10980765-B2 | Isothiocyanatostilbenes as a novel method and product for treating cancer | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) | 2021-04-20 | — | — | US | disclosed |
| US-20190000791-A1 | ISOTHIOCYANATOSTILBENES AS A NOVEL METHOD AND PRODUCT FOR TREATING CANCER | Board of Supervisors for the University of Louisiana System | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10980765-B2 | Isothiocyanatostilbenes as a novel method and product for treating cancer | SI, PCMT1, HDAC8 | TSHR 1944/4885GLA 1191/4885KMT2A 2012/4885 |
| US-20190000791-A1 | ISOTHIOCYANATOSTILBENES AS A NOVEL METHOD AND PRODUCT FOR TREATING CANCER | SI, PCMT1, HDAC8 | TSHR 1944/4885GLA 1191/4885KMT2A 2012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.