⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565787 | 0.74 | — | — | |
| SCHEMBL13884144 | 0.68 | TSHR (0.41) | — | |
| SCHEMBL8536537 | 0.59 | HPGD (0.31) | — | |
| SCHEMBL9865368 | 0.58 | — | — | |
| SCHEMBL11359448 | 0.51 | — | — | |
| SCHEMBL23398385 | 0.50 | GAA (0.38) | — | |
| SCHEMBL7549796 | 0.49 | — | — | |
| SCHEMBL23401212 | 0.49 | — | — | |
| SCHEMBL23398489 | 0.49 | — | — | |
| SCHEMBL12149799 | 0.48 | TDP2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002601-A1 | Method for producing cephalosporins | ACS DOBFAR S.P.A. (IT) | 2004-01-01 | — | — | US | claimed |
| EP-0746561-B1 | QUINOLONYLCARBOXAMIDOCEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ARANDA LAB SA DE CV (MX) | 1999-04-28 | — | — | EP | claimed |
| US-5728691-A | Quinolonylcarboxamidocephalosporin derivatives and pharmaceutical compositions containing them | LABORATORIOS ARANDA S.A. DE C.V. (MX) | 1998-03-17 | — | — | US | claimed |
| EP-0746561-A1 | QUINOLONYLCARBOXAMIDOCEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATORIOS ARANDA, S.A. DE C.V. (MX/MX) (MX) | 1996-12-11 | — | — | EP | claimed |
| WO-1995023153-A1 | QUINOLONYLCARBOXAMIDOCEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATORIOS ARANDA, S.A. DE C.V. (MX) | 1995-08-31 | — | — | WO | claimed |
| EP-0300546-B1 | Process for the preparation of cephem compounds and cephalosporin derivatives | GIST BROCADES NV (NL) | 1995-08-09 | — | — | EP | claimed |
| EP-0074653-B1 | NEW CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-26 | — | — | EP | claimed |
| EP-0099580-B1 | NEW 1-OXA-1-DETHIA-CEPHALOSPORIN DERIVATIVES | MERCK & CO. INC. (US) | 1987-10-14 | — | — | EP | claimed |
| US-4661480-A | Formamido oxacephems | BEECHAM GROUP P.L.C. (GB) | 1987-04-28 | — | — | US | claimed |
| US-4534898-A | 1-Oxa-1-dethia-cephalosporin derivatives | MERCK & CO., INC. (US) | 1985-08-13 | — | — | US | claimed |
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | claimed |
| EP-0031708-B1 | CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR | ICI PHARMA (FR) | 1984-06-13 | — | — | EP | claimed |
| EP-0099580-A1 | New 1-oxa-1-dethia-cephalosporin derivatives | MERCK & CO. INC. (US) | 1984-02-01 | — | — | EP | claimed |
| US-4332800-A | BACTERICIDES CONTAINING 7-AMINOTHIADIAZOLE GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-01 | — | — | US | claimed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | claimed |
| US-20040002601-A1 | Method for producing cephalosporins | ACS DOBFAR S.P.A. (IT) | 2004-01-01 | — | — | US | disclosed |
| EP-0746561-B1 | QUINOLONYLCARBOXAMIDOCEPHALOSPORIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ARANDA LAB SA DE CV (MX) | 1999-04-28 | — | — | EP | disclosed |
| EP-0099580-A1 | New 1-oxa-1-dethia-cephalosporin derivatives | MERCK & CO. INC. (US) | 1984-02-01 | — | — | EP | disclosed |
| EP-0090656-A1 | Penicillins, a process for the preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |