Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599149 | 0.76 | KDM4E (0.57) | ALDH1A1GAAMAPT | |
| SCHEMBL20619706 | 0.72 | KDM4E (0.56) | ALDH1A1GAAMAPTTSHR | |
| SCHEMBL21474618 | 0.70 | GABRP (0.32) | — | |
| SCHEMBL20618442 | 0.69 | PARP10 (0.43) | PARP1PARP10 | |
| SCHEMBL24384849 | 0.68 | BRD4 (0.35) | PARP1PARP10ALDH1A1GAAMAPT | |
| SCHEMBL21471796 | 0.67 | MAPK14 (0.47) | PARP1PARP10ALDH1A1GAAMAPT | |
| SCHEMBL21471733 | 0.63 | NOTUM (0.33) | PARP1PARP10ALDH1A1GAA | |
| SCHEMBL20619601 | 0.63 | KDM4E (0.57) | ALDH1A1GAAMAPT | |
| SCHEMBL20619641 | 0.63 | PIK3CA (0.31) | PARP1PARP10 | |
| SCHEMBL30583047 | 0.61 | PARP10 (0.56) | PARP1PARP10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |