Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619706 | 0.81 | KDM4E (0.56) | NOTUMKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21471602 | 0.80 | GABRP (0.36) | MAPK14NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL21471711 | 0.79 | DHODH (0.34) | MAPK14NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL21471603 | 0.78 | NOTUM (0.38) | NOTUMKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL20599149 | 0.78 | KDM4E (0.57) | MAPK14NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL21471733 | 0.77 | NOTUM (0.33) | NOTUMKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21471613 | 0.77 | NOTUM (0.32) | MAPK14NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL11910393 | 0.75 | NOTUM (0.65) | NOTUMKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21471717 | 0.73 | MAPK14 (0.41) | MAPK14NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL24384846 | 0.72 | NOTUM (0.49) | NOTUMKDM4EALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199908-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |