Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 7/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20599223 | 0.90 | RBP4 (0.41) | VNN1CYP2C9ALDH1A1MAPK1CYP2C19 | |
| SCHEMBL20619918 | 0.80 | SCN10A (0.41) | SCN10AALDH1A1MAPT | |
| SCHEMBL20619566 | 0.79 | HSD17B10 (0.42) | VNN1OPRK1CYP2C9ALDH1A1MAPK1 | |
| SCHEMBL19699773 | 0.76 | RBP4 (0.42) | — | |
| SCHEMBL20618429 | 0.76 | LRRK2 (0.36) | VNN1LRRK2 | |
| SCHEMBL20618190 | 0.73 | ABCC1 (0.37) | VNN1OPRK1SCN10AALDH1A1LRRK2 | |
| SCHEMBL18395148 | 0.71 | PKM (0.47) | ALDH1A1 | |
| SCHEMBL17674350 | 0.68 | OGA (0.38) | VNN1OPRK1 | |
| SCHEMBL17678702 | 0.68 | OGA (0.38) | VNN1OPRK1 | |
| SCHEMBL25389483 | 0.67 | RBP4 (0.44) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |