Imidazole

Imidazole

SCHEMBL2061987

c1c[nH]cn1.c1cnc2c(c1)ccc1ncccc12

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.70
CYP3A4 P08684 2/20 0.49
MAPT P10636 5/20 0.44
KDM4E B2RXH2 4/20 0.44
HSP90AA1 P07900 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
CCR1 P32246 2/20 0.44
CCR5 P51681 2/20 0.44
CCR8 P51685 2/20 0.44
HTT P42858 2/20 0.44
HIF1A Q16665 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
GMNN O75496 1/20 0.44
TP53 P04637 1/20 0.44
MMP2 P08253 1/20 0.44
CYP2D6 P10635 1/20 0.44
MMP9 P14780 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL28724682 1.00 LMNA (0.70) LMNACYP3A4MAPTKDM4EHSP90AA1
Phenanthroline SCHEMBL25421956 0.85 LMNA (0.61) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL6513577 0.83 LMNA (1.00) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL8313 0.83 LMNA (1.00) LMNACYP3A4MAPTKDM4EHSP90AA1
Pyrazine SCHEMBL28719971 0.82 LMNA (0.89) LMNACYP3A4MAPTKDM4EHSP90AA1
Iodide SCHEMBL10638043 0.82 LMNA (0.96) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL723791 0.82 LMNA (0.96) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL3885158 0.82 LMNA (0.96) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL7142651 0.82 LMNA (0.96) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL15788918 0.82 LMNA (0.96) LMNACYP3A4MAPTKDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903137-A Butyl tin-cycloiridium phenanthroline complex with AIE characteristics and preparation method and application thereof 曲阜师范大学 2024-04-19 CN claimed
CN-115490899-B Proton exchange membrane 中国科学院福建物质结构研究所 2024-02-23 CN claimed
CN-115449108-B proton exchange membrane 中国科学院福建物质结构研究所 2023-11-17 CN claimed
CN-114106353-B Four polymerization complexes using phenanthroline imidazole derivative as ligand, preparation method and application thereof 湘潭大学 2023-03-21 CN claimed
CN-115490899-A Proton exchange membrane 中国科学院福建物质结构研究所 2022-12-20 CN claimed
CN-115449108-A Proton exchange membrane 中国科学院福建物质结构研究所 2022-12-09 CN claimed
CN-114106353-A Four polymerization complexes using phenanthroline imidazole derivative as ligand, preparation method and application thereof 湘潭大学 2022-03-01 CN claimed
CN-214633034-U Mesoporous silica composite nanoscale porous microsphere 山东省科学院新材料研究所 2021-11-09 CN claimed
CN-106750194-B Polymeric metal complex containing phenanthroline imidazole derivative and Cd (II), and preparation method and application thereof 湘潭大学 2020-05-22 CN claimed
WO-2016086022-A2 HETEROAROMATIC IMIDAZOLYL COMPOUNDS AND METHODS FOR TREATING CANCER CHANNEL THERAPEUTICS, INC. (US) 2016-06-02 WO claimed
CN-103897681-A Corrosion inhibitor for gas field and preparation method thereof CHINA NAT PETROLEUM CORP 2014-07-02 CN claimed
CN-117903137-A Butyl tin-cycloiridium phenanthroline complex with AIE characteristics and preparation method and application thereof 曲阜师范大学 2024-04-19 CN disclosed
CN-115490899-B Proton exchange membrane 中国科学院福建物质结构研究所 2024-02-23 CN disclosed
CN-115449108-B proton exchange membrane 中国科学院福建物质结构研究所 2023-11-17 CN disclosed
CN-116768920-A Organic copper ion complex antifouling agent and preparation method thereof 洛阳船舶材料研究所(中国船舶集团有限公司第七二五研究所) 2023-09-19 CN disclosed
CN-1087744-C Ruthenium (II) polypyridine match and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2002-07-17 CN disclosed
CN-1289775-A Ruthenium (II) polypyridine match and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2001-04-04 CN disclosed
CN-1289774-A Ruthenium (II) polypyridine match for two-stage pH sensing and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2001-04-04 CN disclosed
CN-1060787-C Thermoplastic resin composition and use thereof MITSUI CHEMICAL CO LTD (JP) 2001-01-17 CN disclosed
CN-1061984-A Thermoplastic resin composition and uses thereof MITSUI PETROCHEMICAL IND (JP) 1992-06-17 CN disclosed